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Ribonuclease P

Author: Fenyong Liu; Sidney Altman
Publisher: New York ; London : Springer, ©2010.
Series: Protein reviews, v. 10.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Ribonuclease P (RNaseP), a ribonucleoprotein, is an essential tRNA processing enzyme found in all living organisms. Since its discovery almost 40 years ago, research on RNase P has led to the discovery of the catalytic properties of RNA, and of the only known, naturally occurring RNA enzymes, RNase P catalytic RNA. The description of the catalytic properties of RNA has provided fundamental insight into the RNA world  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Ribonuclease P.
New York ; London : Springer, ©2010
(OCoLC)528374477
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Fenyong Liu; Sidney Altman
ISBN: 9781441911421 1441911421 1441911413 9781441911414
OCLC Number: 663096170
Description: 1 online resource (xvi, 283 pages) : illustrations (some color).
Contents: History of RNase P and Overview of Its Catalytic Activity --
The Evolution of RNase P and Its RNA --
Over a Decade of Bacterial Ribonuclease P Modeling --
Structural Studies of Ribonuclease P --
Folding of Bacterial RNase P RNA --
Kinetic Mechanism of Bacterial RNase P --
Roles of Metal Ions in RNase P Catalysis --
Challenges in RNase P Substrate Recognition: Considering the Biological Context --
Archaeal RNase P: A Mosaic of Its Bacterial and Eukaryal Relatives --
Eukaryote RNase P and RNase MRP --
RNase P from Organelles --
Human RNase P and Transcription --
RNase P as a Drug Target --
Ribonuclease P as a Tool.
Series Title: Protein reviews, v. 10.
Responsibility: Fenyong Liu, Sidney Altman, editors.

Abstract:

RNaseP is an essential tRNA processing enzyme found in all living organisms. This volume discusses all important aspects of RNaseP structure and function in eukaryotic, prokaryotic, and viral  Read more...

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