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RNA interference technology : from basic science to drug development

Author: Krishnarao Appasani
Publisher: New York : Cambridge University Press, 2004.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. In this cutting-edge overview, the basic concepts of RNAi biology are discussed, as well as the current and potential applications, providing an invaluable reference for all those who need to understand this emerging technology.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
RNA interference technology.
New York : Cambridge University Press, 2004
(DLC) 2004054562
(OCoLC)55962410
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Krishnarao Appasani
ISBN: 0511081766 9780511081767 0511121741 9780511121746
OCLC Number: 122927915
Description: 1 online resource (xxxiii, 510 pages) : illustrations
Contents: Cover; Half-title; Title; Copyright; Dedication; Contents; Foreword; Foreword; Contributors; Introduction; SECTION ONE Basic RNAi, siRNA, microRNAs and gene-silencing mechanisms; SECTION TWO Design, synthesis of siRNAs; SECTION THREE Vector development and in vivo, in vitro and in ovo delivery methods; SECTION FOUR Gene silencing in model organisms; SECTION FIVE Drug target validation; SECTION SIX Therapeutic and drug development; SECTION SEVEN High-throughput genome-wide RNAi analysis; Index.
Responsibility: edited by Krisharao Appasani.

Abstract:

RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. In this cutting-edge overview, the basic concepts of RNAi biology are discussed, as well as the current and potential applications, providing an invaluable reference for all those who need to understand this emerging technology.

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