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Role of Cancer Stem Cells in Cancer Biology and Therapy.

Author: Thomas Dittmar
Publisher: Hoboken : CRC Press, 2013.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiation of cancer relapses. It also examines the dark site of cancer  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Dittmar, Thomas.
Role of Cancer Stem Cells in Cancer Biology and Therapy.
Hoboken : CRC Press, ©2013
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Thomas Dittmar
ISBN: 9781466577367 1466577363 1299704263 9781299704268
OCLC Number: 831118549
Description: 1 online resource (330 pages)
Contents: Front Cover; Preface; Introduction; Contents; Chapter 1 Cancer Stem Cells- Fact or Fiction?; Chapter 2 Cancer Stem Cells of Sarcoma; Chapter 3 Role of Hematopoietic Stem and Progenitor Cells in the Origination of Mature B- cell Lymphomas; Chapter 4 The Leukemia Stem Cell; Chapter 5 CD44 Integrates Signaling in Stem Cell Microenvironments#; Chapter 6 The Dark Site of Conventional Cancer Therapy- Triggering the Origin of Recurrence Cancer Stem Cells; Chapter 7 Current Concepts of How to Eliminate Cancer Stem Cells. Chapter 8 Novel Cancer Therapies by Molecular Targeting Distinct Growth Factor Pathways and Drug Resistance- Associated Molecules in Cancer- and Metastasis- Initiating CellsChapter 9 Salinomycin, a Candidate Drug for the Elimination of Cancer Stem Cells; Chapter 10 Targeting Breast Cancer Stem Cells; Chapter 11 Targeting Leukemic Stem Cells by Breaking Their Dormancy; Color Plate Section; Back Cover.

Abstract:

This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiation of cancer relapses. It also examines the dark site of cancer therapy such as conventional cancer therapies that may lead to the origin of recurrence CSCs. Finally, it supplies a brief overview of current concepts that may allow for a selective er.

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