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Sample sizes for clinical trials

Author: Steven A Julious
Publisher: Boca Raton : CRC Press/Taylor & Francis, ©2010.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"Drawing on various real-world applications, Sample Sizes for Clinical Trials takes readers through the process of calculating sample sizes for many types of clinical trials. It provides descriptions of the calculations with a practical emphasis." "Focusing on normal, binary, ordinal, and survival data, the book explores a range of trials, including superiority, equivalence, non-inferiority, bioequivalence, and  Read more...
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Steven A Julious
ISBN: 9781584887393 1584887397
OCLC Number: 288983232
Description: xxvii, 299 pages : illustrations ; 25 cm
Contents: Seven key steps to cook up a sample size --
Sample sizes for parallel group superiority trials with normal data --
Sample size calculations for superiority cross-over trials with normal data --
Sample size calculations for equivalence clinical trials with normal data --
Sample size calculations for non-inferiority clinical trials with normal data --
Sample size calculations for bioequivalence trials --
Sample size calculations for precision clinical trials with normal data --
Sample size calculations for parallel group superiority clinical trials with binary data --
Sample size calculations for superiority cross-over clinical trials with binary data --
Sample size calculations for non-inferiority trials with binary data --
Sample size calculations for equivalence trials with binary data --
Sample size calculations for precision trials with binary data --
Sample size calculations for clinical trials with ordinal data --
Sample size calculations for clinical trials with survival data.
Responsibility: Steven A. Julious.

Abstract:

Featuring worked examples and problems based on real-world scenarios, this book takes readers through the process of calculating the sample size for various types of clinical trials. It covers the  Read more...

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"... a useful compendium that takes the reader through the process of calculating sample sizes and addresses many points to consider for the most common types of clinical trials and data. ... this Read more...

 
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   schema:reviewBody ""Drawing on various real-world applications, Sample Sizes for Clinical Trials takes readers through the process of calculating sample sizes for many types of clinical trials. It provides descriptions of the calculations with a practical emphasis." "Focusing on normal, binary, ordinal, and survival data, the book explores a range of trials, including superiority, equivalence, non-inferiority, bioequivalence, and precision for both parallel group and cross-over designs. The author discusses how trial objectives impact the study design with respect to the derivation of formulae for sample size calculations. He uses real-life studies throughout to show how the concepts and calculations can be employed."--Jacket." ;
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