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Schizophrenia : evolution and synthesis

Author: Steven M Silverstein; Bita Moghaddam; Til Wykes
Publisher: Cambridge, MA : The MIT Press, [2013]
Series: Strüngmann Forum reports.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical  Read more...
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Genre/Form: Congresses
Document Type: Book
All Authors / Contributors: Steven M Silverstein; Bita Moghaddam; Til Wykes
ISBN: 9780262019620 0262019620
OCLC Number: 842880410
Description: 390 pages ; 24 cm.
Series Title: Strüngmann Forum reports.
Responsibility: edited by Steven M. Silverstein, Bita Moghaddam, and Til Wykes ; program advisory committee: Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Bita Moghaddam, Steven M. Silverstein, Til Wykes.

Abstract:

Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment. The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability.

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There is a wide agreement that schizophrenia remains poorly understood, and this book marvelously summarizes not only the clinical problem, but also the beginnings of a plan for solving it. * Journal Read more...

 
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