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Sensitization of cancer cells for chemo/immuno/radio-therapy

Author: Benjamin Bonavida
Publisher: Totowa, NJ : Humana Press, ©2008.
Series: Cancer drug discovery and development.
Edition/Format:   Print book : EnglishView all editions and formats
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This book reviews novel approaches developed to reverse tumor cell resistance to chemo/immuno/radio-therapy and the use of various sensitizing agents in combination with various cytotoxics. It also  Read more...

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Benjamin Bonavida
ISBN: 9781934115299 1934115290 9781597454742 1597454745
OCLC Number: 209332297
Description: xxi, 419 pages : illustrations.
Contents: Part 1: Sensitization via membrane-bound receptors --
1. Sensitization of epithelial cancer cells with humanm antibodies / H. Peter Vollmers and Stephanie Brandlein --
2. Targeting the transferrin receptor to overcome resistance to anti-cancer agents / Tracy R. Daniels, Isabel I. Neacato, Gustavo Helguera, and Manuel L. Penichet --
3. Chemo-immunosensitization of resistant B-NHL as a result of Rituximab (anti-CD20 mAb)-mediated inhibition of cell survival signaling pathways / Benjamin Bonavida, Ali R. Jazirehi, Mario I. Vega, Sara Huerta-Yepez, Kazuo Umezawa, and Eriko Suzuki --
4. Agents that regulate DR5 and sensitivity to TRAIL / Tatsushi Yoshida and Toshiyuki Sakai --
5. Proteasome inhibition : potential for sensitization of immune effector mechanisms in cancer / Milad Motarjemi, William H.D. Hallett, Minghui Li, and William J. Murphy --
Part II : Sensitization via inhibition of cell survival pathways (excluding apoptotic signaling pathways) --
6. Angiogenesis inhibitors as enabling agents for the chemotherapeutic treatment of metastatic disease / Giulio Francia, Urban Emmenegger, and Robert S. Kerbel --
7. Targeting survival cascades induced by activation of Ras-Raf-MEK-ERK and PI3K-Akt pathways to sensitize cancer cells to therapy / James A. McCubrey, Richard A. Franklin, Fred E. Bertrand, Jackson R. Taylor, William H. Chappell, Melissa L. Midgett, Ellis W.T. Wong, Stephen L. Abrams, Kristin M. Stadelman, Negin Misaghian, Dale L. Ludwig, Jorg Basecke, Massimo Libra, Franca Stivala, Michele Milella, Agostino Tafuri, Alberto M. Martelli, Paolo Lungi, Antonio Bonati, David M. Terrian, Brian D. Lehmann, and Linda S. Steelman --
8. Histone deacetylase inhibitors and anticancer activity / Roberto R. Rosato and Steven Grant --
9. Eicosanoids and Resistance of Cancer Cells to Chemotherapeutic Agents / Andrey Sorokin --
Part III : Sensitization via transcription factors --
10. The RKIP and STAT3 axis in cancer chemotherapy : opposites attract / Devasis Chatterjee, Edmond Sabo, Murray B. Resnick, Kam C. Yeung, and Y. Eugene Chin --
11. Targeting transcription factors with decoy oligonucleotides : modulation of the expression of genes involved in chemotherapy resistance of tumor cells / Roberto Gambari --
12. p53 inhibitors as cancer sensitizing a agents / Flavio Maina and Rosanna Dono --
13. Nitric Oxide-Induced immunosensitization to apoptosis by Fas-L and TRAIL / Benjamin Bonavida, Sara Huerta-Yepez, Mario I. Vega, Demetrios A. Spandidos, and Stravoula Baritaki --
14. Natural agents that can sensitize tumor cells to chemotherapy and radiation therapy / Ganesh Jagetia, Sunil Krishnan, and Bharat B. Aggarwal --
Part IV : Sensitization via targeting apoptotic pathways --
15. Inhibitors of the Bcl-2 protein family as sensitizers to anticancer agents / Daniel E. Johnson --
16. Therapeutic targeting of apoptosis in cancer / Timothy R. Wilson, Daniel B. Longley, and Patrick G. Johnston --
17. Peptides and peptidomimetics as cancer therapy sensitizing agents / Shantanu Banerji, Sudharsana Rao Ande, Subbareddy Maddika, Versha Banerji, Iran Rashedi, Neil W. Owens, Anne Zuse, Frank Schweizer, and Marek Los --
18. Non-Peptidic mimetics as cancer-sensitizing agents / Ruud P.M. Dings, Mark Klein, and Kevin H. Mayo --
19. Sensitization of cancer cells to cancer therapies by isofl avone and Its synthetic derivatives / Fazlul H. Sarkar and Yiwei Li --
20. Antisense oligonucleotides and siRNA as specific inhibitors of gene expression : mechanisms of action and therapeutic potential / Yvonne Forster and Bernd Schwenzer --
Part V : Sensitization tailored to individual patients --
21. DNA polymorphisms affecting chemosensitivity toward drugs / Thomas Efferth and Michael Wink --
22. Pharmacogenetics in cancer management : scenario for tailored therapy / Erika Cecchin, Massimo Libra, Calogero Cannavo, Bibiana Bruni, Alberto Fulvi, Giuseppe Toffoli, and Franca Stivala.
Series Title: Cancer drug discovery and development.
Responsibility: edited by Benjamin Bonavida.
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From the reviews:"This book introduces emerging strategies, potential signaling pathways and biomolecules as key targets to sensitize resistant cancers. ... detailed information and data can be Read more...

 
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