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Sialo-xenoantigenic glycobiology : molecular glycobiology of sialylglycan-xenoantigenic determinants in pig to human xenotransplantation.

Author: Kwon-Ho Song; Cheorl-Ho Kim
Publisher: Heidelberg ; New York : Springer, ©2013.
Series: Sungkyunkwan University outstanding research, 1.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Carbohydrate antigens on glycoconjugates of mammalian cells play crucial roles in various biological processes and are epitopes recognized by the immune system, as glycobiology has hugely been progressed during the past two decades. The book focuses on sialic acid-based xenoantigenes. In pig to human xenotransplantation, exposure of pig organs to human blood results in hyper acute rejection (HAR), caused by  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Song, Kwon-Ho.
Sialo-xenoantigenic glycobiology.
Heidelberg ; New York : Springer, ©2013
(DLC) 2012949130
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Kwon-Ho Song; Cheorl-Ho Kim
ISBN: 9783642340949 3642340946
OCLC Number: 821265731
Description: 1 online resource : illustrations.
Contents: Screening of Pig Glycosyltransferase Genes Related to Xenoantigens and Their Masking --
Cloning and Tissue Specific Expression of pcmah and Its Alternative Transcripts --
Functional Characterization of pCMAH in the Synthesis of N-Glycolylneuraminic Acid as the Xenoantigenic Determinant in Pig-to-Human Xenotransplantation --
Identification of Two Alternative Promoters of the Pig CMP-N-Acetylneuraminic Acid Hydroxylase Gene --
Screening for Xenoantigenic Determinants Formed by Sialyltransferases.
Series Title: Sungkyunkwan University outstanding research, 1.

Abstract:

The latest advances from leading experts in this vital field of medical endeavor comprise the core value of this book, which focuses on the molecular biology of carbohydrate antigens, including  Read more...

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