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Signal transduction

Author: B D Gomperts; Peter E R Tatham, (Life scientist); Ijsbrand M Kramer
Publisher: Amsterdam ; Boston : Elsevier/Academic Press, ©2009.
Edition/Format:   eBook : Document : English : 2nd edView all editions and formats
Summary:
Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention * In-depth coverage of nuclear receptors, including steps in isolation of steriod hormones and the discovery of intracellular hormone receptors; Tyrosine protein kinases and adaptive immunity; and intracellular calcium * Extensive conceptual colour artwork to assist with comprehension of key topics * Instrumental  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Gomperts, B.D.
Signal transduction.
Amsterdam ; Boston : Elsevier/Academic Press, ©2009
(OCoLC)373478545
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: B D Gomperts; Peter E R Tatham, (Life scientist); Ijsbrand M Kramer
ISBN: 9780080568775 0080568777 9780080919058 0080919057 9780123948199 0123948193
OCLC Number: 528609561
Description: 1 online resource (xxvii, 810 pages) : color illustrations
Contents: Prologue: Signal Transduction, origins and ancestors --
First messengers --
Receptors --
GTP-binding proteins and signal transduction --
Effector enzymes coupled to GTP binding proteins: adenylyl cyclase and phospholipase C --
The regulation of visual transduction and olfaction --
Intracellular calcium --
Calcium effectors --
Phosphorylation and dephosphorylation: protein kinases A and C --
Nuclear receptors --
Growth Factors: Setting the framework --
Signalling pathways operated by receptor protein tyrosine kinases --
Signal transduction to and from adhesion molecules --
Adhesion molecules in the regulation of cell differentiation: Mainly about Wnt --
Activation of the innate immune system: the Toll-like receptor 4 and Signalling through Ubiquitylation --
Traffic of white blood cells --
Tyrosine protein kinases and adaptive immunity : TCR, BCR, soluble tyrosine kinases and NFAT --
Phosphoinositide 3-kinases, protein kinase B and signalling through the insulin receptor --
Protein Kinase C revisited --
Signalling through receptor serine/threonine kinases --
Protein dephosphorylation and protein phosphorylation --
Notch --
Targeting transduction pathways for research and medical intervention --
Protein domains and signal transduction.
Responsibility: Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham.

Abstract:

Presents a study in cellular signaling processes. This book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and instructs how these inputs are  Read more...

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