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Small molecule medicinal chemistry : strategies and technologies

Author: Werngard Czechtizky; Peter Hamley
Publisher: Hoboken, New Jersey : John Wiley & Sons, 2015.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

Stressing strategic and technological solutions to medicinal chemistry challenges, this book presents methods and practices for optimizing the chemical aspects of drug discovery. It provides an  Read more...

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Genre/Form: Electronic books
Additional Physical Format: Print version:
Small molecule medicinal chemistry.
Hoboken, New Jersey : John Wiley & Sons, 2015
(DLC) 2015020801
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Werngard Czechtizky; Peter Hamley
ISBN: 9781118771570 1118771575 9781118771693 1118771699 9781118771723 1118771729 1118771605 9781118771600
OCLC Number: 911135112
Description: 1 online resource
Contents: Elements for the development of strategies for compound library enhancement / Edgar Jacoby --
The European lead factory / Christopher Kallus, Jörg Hüser, Philip S. Jones, Adam Nelson --
Access to compound collections : new business models for compound acquisition and sharing / Peter ten Holte --
New advances in diversity-oriented synthesis / Warren R.J.D. Galloway, Jamie E. Stokes, David R. Spring --
Solid-phase combinatorial chemistry : ready for a revival? / Marcel Patek, Martin Smrcina, Eric Wegrzyniak, Victor Nikolaev, Andres Mariscal --
Recent advances in multicomponent reaction chemistry : applications in small molecule drug discovery / Christopher Hulme, Muhammad Ayaz, Guillermo Martinez-Ariza, Federico Medda, Arthur Shaw --
Computational techniques to support hit triage / Douglas B. Kitchen, Hélène Y. Decornez --
Fragment-based drug discovery / Jean-Paul Renaud, Thomas Neumann and Luc Van Hijfte --
Virtual screening / Karl-Heinz Baringhaus, Gerhard Hessler --
Phenotypic screening / Michelle Palmer --
Advances in the understanding of drug properties in medicinal chemistry / Peter Hamley, Patrick Jimonet --
Recent developments in automated solution phase library production / Thomas C. Maier, Werngard Czechtizky --
Adme profiling : an introduction for the medicinal chemist / Katharina Mertsch, Martin Will, Werngard Czechtizky, Niels Griesang, Alexander Marker, Jacob Olsen --
The role of natural products in drug discovery : examples of marketed drugs / Lars Ole Haustedt and Karsten Siems --
Peptidomimetics of a-helical and b-strand protein binding epitopes / Nina Bionda, Rudi Fasan --
In vivo imaging of drug action / Oliver Plettenburg, Matthias Löhn.
Responsibility: edited by Werngard Czechtizky, Peter Hamley.

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"This book describes a large variety of methodologies that are employed in drug discovery and early development. The subjects covered range from the design and administration of chemical libraries, Read more...

 
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