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Solvent systems and their selection in pharmaceutics and biopharmaceutics
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Solvent systems and their selection in pharmaceutics and biopharmaceutics

Author: Patrick Augustijns; Marcus Brewster; American Association of Pharmaceutical Scientists.
Publisher: New York, NY : Springer/AAPS Press, 2007.
Series: Biotechnology (Arlington, Va.), v. 6.
Edition/Format:   Book : Document   Computer File : EnglishView all editions and formats
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Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics

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Material Type: Document, Internet resource
Document Type: Book, Computer File, Internet Resource
All Authors / Contributors: Patrick Augustijns; Marcus Brewster; American Association of Pharmaceutical Scientists.
ISBN: 9780387691497 0387691499 9780387691541 0387691545
OCLC Number: 123374507
Description: viii, 459 p. : ill.
Contents: Introduction.- Principles of Solubility.- Ionic Equilibria and the pH Dependence of Solubility.- Solvent Systems for Crystallisation, Recrystallisation and Polymorph Selection.- Solvent Issues in Early Discovery and HTS.- Solubility Determination in Pharmaceutical Preformulation.- Systems for Determination of Bio-Relevant Dissolution.- Selection of Solvent Systems for Membrane-, Cell- and Tissue-Based Permeability Estimation.- Tox-Vehicles for Contemporary Pipelines.- Solubilizing Vehicles for Oral Formulation Development.- Solubilizing Systems for Parenteral Formulation Development -- Small Molecules.- Aqueous Solubilizing Systems for Parenteral Formulation Development -- Proteins.- Non-Aqueous Solubilizing Systems for Parenteral Formulation Development -- Proteins.- Pharmaceutical Solvents as Vehicles for Topical Dosage Forms.- Pharmaceutical Solvents as Vehicles for Pulmonary Formulations.
Series Title: Biotechnology (Arlington, Va.), v. 6.
Responsibility: [edited by] Patrick Augustijns, Marcus Brewster.
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