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| Material Type: | Document, Internet resource |
|---|---|
| Document Type: | Book, Computer File, Internet Resource |
| All Authors / Contributors: |
Patrick Augustijns; Marcus Brewster; American Association of Pharmaceutical Scientists. |
| ISBN: | 9780387691497 0387691499 9780387691541 0387691545 |
| OCLC Number: | 123374507 |
| Description: | viii, 459 p. : ill. |
| Contents: | Introduction.- Principles of Solubility.- Ionic Equilibria and the pH Dependence of Solubility.- Solvent Systems for Crystallisation, Recrystallisation and Polymorph Selection.- Solvent Issues in Early Discovery and HTS.- Solubility Determination in Pharmaceutical Preformulation.- Systems for Determination of Bio-Relevant Dissolution.- Selection of Solvent Systems for Membrane-, Cell- and Tissue-Based Permeability Estimation.- Tox-Vehicles for Contemporary Pipelines.- Solubilizing Vehicles for Oral Formulation Development.- Solubilizing Systems for Parenteral Formulation Development -- Small Molecules.- Aqueous Solubilizing Systems for Parenteral Formulation Development -- Proteins.- Non-Aqueous Solubilizing Systems for Parenteral Formulation Development -- Proteins.- Pharmaceutical Solvents as Vehicles for Topical Dosage Forms.- Pharmaceutical Solvents as Vehicles for Pulmonary Formulations. |
| Series Title: | Biotechnology (Arlington, Va.), v. 6. |
| Responsibility: | [edited by] Patrick Augustijns, Marcus Brewster. |
| More information: |
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