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Some Current Concepts of Synaptic Organization

Author: David Gareth Jones
Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 1978.
Series: Advances in Anatomy, Embryology and Cell Biology / Ergebnisse der Anatomie und Entwicklungsgeschichte / Revues d'anatomie et de morphologie expérimentale, 55/4; Advances in Anatomy, Embryology and Cell Biology / Ergebnisse der Anatomie und Entwicklungsgeschichte / Revues d'anatomie et de morphologie expérimentale, 55/4.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
The accumulation of literature dealing with the structure and function of synapses presents the synaptologist with a formidable problem. The diverse interests now en compassed by synaptology, and the many facets of neurobiology mirrored in these interests, make the task of reviewing synaptic organization a major one. Selection must be made and, if the reader is not to be misled, biases must be exposed. My frame of  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: David Gareth Jones
ISBN: 9783642670695 3642670695 9783540090113 3540090118
OCLC Number: 858929695
Description: 1 online resource.
Contents: 1. Introduction --
2. Outline of Synaptic Morphology --
2.1. Synaptic Parameters --
2.2. Synaptic Variation --
3. Issues in Synaptic Terminal Organization --
3.1. Vesicle-Membrane Relationships --
3.2. Microfilamentous Network --
3.3. Coated Vesicles --
3.4. Protein Composition of the Junctional Region --
3.5. Microtubular System --
4. Models of the Presynaptic Terminal --
Summary --
References.
Series Title: Advances in Anatomy, Embryology and Cell Biology / Ergebnisse der Anatomie und Entwicklungsgeschichte / Revues d'anatomie et de morphologie expérimentale, 55/4; Advances in Anatomy, Embryology and Cell Biology / Ergebnisse der Anatomie und Entwicklungsgeschichte / Revues d'anatomie et de morphologie expérimentale, 55/4.
Responsibility: by David Gareth Jones.
More information:

Abstract:

The accumulation of literature dealing with the structure and function of synapses presents the synaptologist with a formidable problem. The diverse interests now en compassed by synaptology, and the many facets of neurobiology mirrored in these interests, make the task of reviewing synaptic organization a major one. Selection must be made and, if the reader is not to be misled, biases must be exposed. My frame of reference is the presynaptic terminal, that is, the enlarged termination of the axon (Figs. 1 and 2). This includes the specialized presynaptic membrane run ning alongside the cleft region and associated with the dense projections and presyn- tic vesicular grid (Figs. 1 and 8). Within the cytoplasm of the terminal are the synaptic and coated vesicles, mitochondria, the micromamentous presynaptic network and possibly microtubules. My approach to the presynaptic terminal will rely principally on mor phological concepts, although biochemical features of the composition of the ju- tional region are essential for a basic understanding of synaptic organization and ref erence to these will also be made.

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