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Some drugs and herbal products.

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Meeting
Publisher: Lyon, France : International Agency for Research on Cancer, 2016.
Series: IARC monographs on the evaluation of carcinogenic risks to humans, v. 108.
Edition/Format:   eBook : Document : Conference publication : International government publication : EnglishView all editions and formats
Database:WorldCat
Summary:
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 14 drugs and herbal products. The IARC Monographs Working Group relied on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used  Read more...
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Genre/Form: Evaluation Studies
Congresses
Material Type: Conference publication, Document, Government publication, International government publication, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Meeting
ISBN: 9789283201748 9283201744 9789283201465 9283201469
OCLC Number: 949752486
Description: 1 online resource (1 PDF file (xii, 422 pages)) : illustrations (some color).
Contents: Note to the reader --
List of participants --
Preamble --
General remarks --
Aloe vera --
Goldenseal --
Gingko biloba --
Kava --
Pulegone --
Methylene blue --
Primidone --
Sulfasalazine --
Pentosan polysulfate sodium --
Triamterene --
Hydrochlorothiazide --
Pioglitazone and rosiglitazone --
Digoxin --
List of abbreviations.
Series Title: IARC monographs on the evaluation of carcinogenic risks to humans, v. 108.

Abstract:

This volume of the IARC Monographs provides an assessment of the carcinogenicity of 14 drugs and herbal products. The IARC Monographs Working Group relied on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension). Other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): Aloe vera whole leaf extract, goldenseal root powder, Ginkgo biloba leaf extract, kava extract, and pulegone. In view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans.

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