skip to content
Sphingolipids : basic science and drug development Preview this item
ClosePreview this item
Checking...

Sphingolipids : basic science and drug development

Author: Erich Gulbins; Irina Petrache
Publisher: Vienna ; New York : Springer, ©2013.
Series: Handbook of experimental pharmacology, v.215.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

 

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Erich Gulbins; Irina Petrache
ISBN: 9783709113684 3709113687
OCLC Number: 840600290
Notes: Includes index.
Description: 1 online resource.
Contents: Part I Basic Mechanisms. The Genetics of Sphingolipid Hydrolases and Sphingolipid Storage Diseases / Edward H. Schuchman, Calogera M. Simonaro --
Sphingolipids and Membrane Domains: Recent Advances / Salvatore Chiantia, Erwin London --
Sphingolipid Metabolism and Neutral Sphingomyelinases / Michael V. Airola, Yusuf A. Hannun --
Acid Sphingomyelinase / Brian Henry ... [et al.] --
Ceramide Synthases: Reexamining Longevity / Joo-Won Park, Yael Pewzner-Jung --
Membrane Channels Formed by Ceramide / Marco Colombini --
Genetic Disorders of Simple Sphingolipid Metabolism / Virginie Albinet ... [et al.] --
The Role of Ceramide-1-Phosphate in Biological Functions / L. Alexis Hoeferlin, Dayanjan S. Wijesinghe, Charles E. Chalfant --
Part II Drug Development. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) / Johannes Kornhuber ... [et al.] --
Novel Drugs Targeting Sphingolipid Metabolism / Krishna P. Bhabak, Christoph Arenz --
The Therapeutic Potential of Nanoscale Sphingolipid Technologies / Jody L. Hankins ... [et al.] --
Novel Chemotherapeutic Drugs in Sphingolipid Cancer Research / Daniel Canals, Yusuf A. Hannun --
Pharmacology of the Sphingosine-1-Phosphate Signalling System / Dagmar Meyer zu Heringdorf, Katja Ihlefeld, Josef Pfeilschifter.
Series Title: Handbook of experimental pharmacology, v.215.
Responsibility: Erich Gulbins, Irina Petrache, editors.

Abstract:

This book examines the physiological and pathophysiological role of sphingolipids and their derivative ceramide, and their function in cell signalling, tumor metastasis, cardiovascular disease and  Read more...

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


<http://www.worldcat.org/oclc/840600290>
library:oclcnum"840600290"
library:placeOfPublication
library:placeOfPublication
library:placeOfPublication
rdf:typeschema:MediaObject
rdf:typeschema:Book
rdf:valueUnknown value: dct
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:bookFormatschema:EBook
schema:contributor
schema:contributor
schema:copyrightYear"2013"
schema:datePublished"2013"
schema:description"Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids' basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context."@en
schema:exampleOfWork<http://worldcat.org/entity/work/id/1254511534>
schema:genre"Electronic books"@en
schema:inLanguage"en"
schema:isPartOf
schema:name"Sphingolipids basic science and drug development"@en
schema:publication
schema:publisher
schema:url<http://site.ebrary.com/id/10691409>
schema:url<http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=579338>
schema:url<http://lib.myilibrary.com?id=485506>
schema:url<http://oclc-marc.ebrary.com/Doc?id=10691409>
schema:url<http://dx.doi.org/10.1007/978-3-7091-1368-4>
schema:workExample
wdrs:describedby

Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.