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St. John's Wort and its active principles in depression and anxiety

Author: Walter E Müller
Publisher: Basel ; Boston : Birkhäuser, ©2005.
Series: Milestones in drug therapy.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
"This book reviews the available data related to the biochemical, functional, and behavioural pharmacology of Hypericum and its active constituents. The clinical chapters overview the evidenced basis for its use as an antidepressant, initial data in anxiety and somatoform disorders, and the site effect profile of Hypericum and its possible relevant drug interactions. The known pharmacokinetics of the relevant  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
St. John's Wort and its active principles in depression and anxiety.
Basel ; Boston : Birkhäuser, ©2005
(DLC) 2004062277
(OCoLC)57002125
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Walter E Müller
ISBN: 3764361603 9783764361600 3764373385 9783764373382
OCLC Number: 62767192
Description: 1 online resource (viii, 188 pages) : illustrations.
Contents: And historical overview --
Phytochemistry --
St. John's Wort and its active principles in depression and anxiety --
A critical analysis of receptor binding studies --
Effects on transmitter uptake and their cellular and molecular basis --
Modulation of neurotransmitter release and metabolism --
Efficacy in behavioural models of antidepressant activity --
Comparative preclinical antidepressant activity of isolated constituents --
Hyperforin and efficacy in animal models for anxiety and cognition --
Pharmacokinetics and biopharmaceuticals --
Clinical efficacy in depression --
Clinical efficacy of St. John's Wort in psychiatric disorders other than depression --
Side effects and drug interactions --
Endocrinology of St. John's Wort extract.
Series Title: Milestones in drug therapy.
Responsibility: edited by W.E. Müller.
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Abstract:

The clinical chapters overview the evidenced basis for its use as an antidepressant, initial data in anxiety and somatoform disorders, and the site effect profile of Hypericum and its possible  Read more...

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From the reviews:...this book presents an excellent account of experimental as well as clinical research that has been done on St. John's wort. Not only have the authors been successful in presenting Read more...

 
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