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Structural insights into aminoacyl-tRNA delivery by EF-Tu and translocation by EF-G

Author: J Frank
Publisher: London : Henry Stewart Talks, 2008.
Series: Henry Stewart talks., Biomedical & life sciences collection., Mechanisms of ribosome function : insights into protein synthesis.
Edition/Format:   eVideo : Clipart/images/graphics : EnglishView all editions and formats
Summary:
Audio-visual presentation: Schematic of elongation cycle -- Role of elongation factors EF-G and EF-Tu -- Molecular mimicry of elongation factors -- Binding positions of factors and tRNA during elongation cycle -- Process of tRNA selection -- Proofreading -- Role of bases A1492 and A1493 -- GTP hydrolysis on EF-Tu -- tRNA as a molecular spring -- Translocation -- Intersubunit ratchet motion -- Induced fit -- FRET  Read more...
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Details

Material Type: Clipart/images/graphics, Internet resource, Videorecording
Document Type: Internet Resource, Computer File, Visual material
All Authors / Contributors: J Frank
OCLC Number: 310381962
Notes: Title from title frames.
Animated audio-visual presentation with synchronized narration.
Description: 1 streaming video file (27 min.) : digital, mono, SWF file, sound, color.
Details: Mode of access: World Wide Web.; System requirements: Operating System: PC Windows 2000+, Mac OSX+ 3.2. Browser Compatibility: IE6+, Firefox 2+, Opera 9+, Safari 2+ 3.3. Browser settings: enable JavaScript, enable popups from the Henry Stewart Talks site. 3.4. Required Browser Plugins & Viewers: Adobe (Macromedia) Flash Player 7+, Adobe Acrobat Reader6.0+.
Contents: Schematic of elongation cycle --
Role of elongation factors EF-G and EF-Tu --
Molecular mimicry of elongation factors --
Binding positions of factors and tRNA during elongation cycle --
Process of tRNA selection --
Proofreading --
Role of bases A1492 and A1493 --
GTP hydrolysis on EF-Tu --
tRNA as a molecular spring --
Translocation --
Intersubunit ratchet motion --
Induced fit --
FRET studies of ratchet motion --
Hybrid states of tRNA --
Role of GTP hydrolysis in translocation.
Series Title: Henry Stewart talks., Biomedical & life sciences collection., Mechanisms of ribosome function : insights into protein synthesis.
Responsibility: Joachim Frank.
More information:

Abstract:

Audio-visual presentation: Schematic of elongation cycle -- Role of elongation factors EF-G and EF-Tu -- Molecular mimicry of elongation factors -- Binding positions of factors and tRNA during elongation cycle -- Process of tRNA selection -- Proofreading -- Role of bases A1492 and A1493 -- GTP hydrolysis on EF-Tu -- tRNA as a molecular spring -- Translocation -- Intersubunit ratchet motion -- Induced fit -- FRET studies of ratchet motion -- Hybrid states of tRNA -- Role of GTP hydrolysis in translocation.

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