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Structure and control

Author: Paul D Boyer
Publisher: New York ; London : Academic Press, 1970.
Series: Enzymes, v. 1.
Edition/Format:   eBook : Document : English : 3rd edView all editions and formats
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Structure and control.
New York ; London : Academic Press, 1970
(OCoLC)16765751
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Paul D Boyer
ISBN: 9780080865782 008086578X
OCLC Number: 298615056
Description: 1 online resource (xvi, 559 pages) : illustrations.
Contents: Front Cover; The Enzymes Structure and Control, Volume I; Copyright Page; Contents; List of Contributors; Preface; Contents of Other Volumes; Chapter 1. X-Ray Crystallography and Enzyme Structure; I. Introduction; II. Enzyme Crystals; III. X-Ray Diffraction and Principles of Protein Structure Analysis; IV. X-Ray Diffraction Studies of Globular Macromolecules; V. Summary and Conclusions; Glossary of Symbols; Chapter 2. Chemical Modification by Active-Site-Directed Reagents; I. Nature of Affnnity Labeling and Its Relationship to Chemical Modification in General. II. Modification of Serine Proteases by Active-Site-Directed ReagentsIII. Active Center Labeling of Other Enzymes by Directed Reagents; IV. Particular Usefulness of Active-Site-Directed Reagents; V. Conclusions; Chapter 3. Chemical Modification as a Probe of Structure and Function; I. Introduction; II. Principles of Chemical Modification; III. Methodology; IV. Modification as a Probe of Structure; V. Modification as a Probe of Function; VI. Other Uses of Chemical Modification; VII. Discussions of Specific Enzymes; VIII. Conclusions; Chapter 4. Multienzyme Complexes; I. Introduction. II. a-Ketoacid Dehydrogenase ComplexesIll. Fatty Acid Synthetases; IV. Multienzyme Complexes in the Biosynthesis of Aromatic Amino Acids; V. Biological Significance of Multienzyme Complexes; Chapter 5. Genetic Probes of Enzyme Structure; I. Introduction; II. Genes and Mutations; III. Specific Examples of Mutationally Altered Proteins; IV. Amino Acid Analogs; V. Advantages and Limitations of Mutants; Chapter 6. Evolution of Enzymes; I. General Considerations-Evolutionary and Structure-Function Relationships in Proteins; II. Some Principles from the Study of Cytochrome c. III. Expressions of Genetic Phenomena in Protein StructureIV. Expression of Evolutionary Factors in Protein Structure; Chapter 7. The Molecular Basis for Enzyme Regulation; I. Introduction; II. Qualitative Features of Molecular Models; III. Quantitative Molecular Parameters for Regulatory Proteins; IV. Diagnostic Tests; V. Molecular Properties of Allosteric Proteins; VI. Conclusions; VII. Glossary; Chapter 8. Mechanisms of Enzyme Regulation in Metabolism; I. Introduction; II. Principles of Metabolic Regulation; III. Regulation of Balance between Metabolic Functions. IV. Feedback Regulation of Multifunctional PathwaysChapter 9. Enzvmes as Control Elements in Metu bolic Regulation; I. Introduction; II. Analogy between Metabolic and Electronic Systems; III. Physiological Function and Design Requirements; IV. Summary; Author Index; Subject Index.
Series Title: Enzymes, v. 1.
Responsibility: edited by Paul D. Boyer.

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