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Structure-function analysis of G protein-coupled receptors

Author: Jürgen Wess
Publisher: New York : Wiley-Liss, ©1999.
Series: Receptor biochemistry and methodology (Unnumbered)
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
This volume provides a concise, up-to-date presentation of methods (including molecular, genetic, biochemical, and biophysical) which have been used successfully in studying the structure and function of GPCRs. With contributions from international leaders in the field, the editor provides overviews of various techniques, followed by in-depth descriptions of basic procedures and discussions of critical experimental  Read more...
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Additional Physical Format: Online version:
Structure-function analysis of G protein-coupled receptors.
New York : Wiley-Liss, ©1999
(OCoLC)606386031
Online version:
Structure-function analysis of G protein-coupled receptors.
New York : Wiley-Liss, ©1999
(OCoLC)607665622
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Jürgen Wess
ISBN: 047125228X 9780471252283 0471252271 9780471252276
OCLC Number: 40150649
Description: xii, 412 pages : illustrations ; 26 cm.
Contents: 1. Overview of Mutagenesis Techniques / Tung Ming Fong --
2. The Substituted-Cysteine Accessibility Method / Jonathan A. Jovitch --
3. Using Mutagenesis to Map the Binding Domains of Small Molecule Receptors / Jean E. Lachowicz and Catherine D. Strader --
4. Mapping Binding Sites for Peptide G Protein-Coupled Receptors: The Receptor for Thyrotropin-Releasing Hormone / Roman Osman, Anny-Odile Colson and Jeffrey H. Perlman / [and others] --
5. Lessons From Rhodopsin / Thomas P. Sakmar and K. Christopher Min --
6. Split Receptors as Tools for Analyzing G Protein-Coupled Receptor Structure / Masahiro Kono and Daniel D. Oprian --
7. Metal-Ions as Atomic Scale Probes of G Protein-Coupled Receptor Structure / John A. Schetz and David R. Sibley.
Series Title: Receptor biochemistry and methodology (Unnumbered)
Responsibility: edited by Jürgen Wess.
More information:

Abstract:

G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions.  Read more...

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