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Studies in Natural Products Chemistry.

Author: Atta-ur-Rahman.
Publisher: San Diego : Elsevier Science, 2018.
Series: Studies in natural products chemistry.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Studies in Natural Products Chemistry, Volume 58, covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Atta-ur-Rahman.
Studies in Natural Products Chemistry.
San Diego : Elsevier Science, ©2018
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Atta-ur-Rahman.
ISBN: 9780444640598 0444640592 9780444641809 0444641807
OCLC Number: 1023529195
Notes: Starting From Geniposide.
Description: 1 online resource (494 pages).
Contents: Front Cover; Studies in Natural Products Chemistry; Copyright; Contents; Contributors; Preface; Chapter 1: Novel Approaches in the Synthesis of Natural and Synthetic Fused Aza-Polycycles Toward the Development of New ... ; Introduction; Synthesis and Biological Properties of Tetrahydroisoquinoline Alkaloids; 1-Phenethyltetrahydroisoquinolines: The Challenge to Control the Stereochemistry of the C-1 Center; Current Strategies for the Synthesis of Aporphine and Homoaporphine Alkaloids. β-Carboline Alkaloids Isolated From Marine Invertebrates and Plant Sources: Synthesis and Biological ApplicationsHarmala Alkaloids and Their Synthetic Derivatives; Eudistomin Alkaloids and Their Biological Activities; Conclusions and Perspectives; Acknowledgments; References; Chapter 2: Combretastatins: Plant Anticancer Phenolics; Introduction; Chemical Structure; Structure-Activity Relationship; Mode of Antitumor Action; Mechanism of CA-4P Antivascular Effects; CA-4P in the Clinical Setting; Phase I Studies; Phase II/III Studies; Adverse Effects of CA-4P; Analogues and Derivatives of CA-4. Alternative Drug Delivery SystemsConcluding Remarks; References; Further Reading; Chapter 3: The Role of Natural Products in Alzheimer's and Parkinson's Disease; Introduction; Alzheimer's Disease; Natural Products and Their Bioactivity Against AD; Terpenoids; Phenolics; Alkaloids; Lignans; Withanolides; Coumarins; Parkinson's Disease; Natural Products and Their Bioactivity Against Parkinson's Disease; Miscellaneous Compounds; Conclusion; References; Chapter 4: Nature's Medicines to Treat Epileptic Seizures; Introduction; Epilepsy Stats; Pathophysiology and Treatment of Epilepsy. Epileptic Rodent ModelsSearch for New Anticonvulsants; D. denudatum; Delphinium nordhagenii; F. religiosa L.; N. alba Linnaeus; A. marmelos; Other Plant Species; Conclusion; Acknowledgment; References; Chapter 5: Effects of Bioactive Components of Green Tea on Alzheimer's Disease; Introduction; Alzheimer's Disease; Bioactive Ingredients of Green Tea; Possible Mechanisms From Experimental Studies; Antioxidative Stress Effects; Antiinflammatory Effects; Activation of the PKC Pathway; Acetylcholinesterase Inhibition; Other Predicted Mechanisms; Clinical Studies Focused on Tea and AD. Cross-Sectional StudiesLongitudinal Studies; Interventional Studies; Discussion and Future Perspectives; Conclusions; Acknowledgments; Contributions; References; Chapter 6: Anti-HIV Agents From Nature: Natural Compounds From Hypericum hircinum and Carbocyclic Nucleosides From Iridoids; Introduction; Natural Anti-HIV Agents; H. hircinum as Natural Source of Anti-HIV Agents; Carbocyclic Nucleoside Analogues Anti-HIV Agents From Iridoids; Carbocyclic Nucleoside Analogues; Partial Synthesis From Iridoid Glucosides to Carbocyclic Nucleosides as New Anti-HIV Agents; Starting From Aucubin.
Series Title: Studies in natural products chemistry.

Abstract:

Studies in Natural Products Chemistry, Volume 58, covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry.

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