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Sumoylation : molecular biology and biochemistry

Author: Van Gene Wilson
Publisher: Wymondham, Norfolk, U.K. : Horizon Bioscience, ©2004.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
This volume presents information on the history, evolution and mechanisms of sumoylation, discusses SUMO proteases, ligases and conjugation pathways, and reviews the impact on modification and nucleocytoplasmic transport, PML nuclear bodies, and transcriptional regulation. Specialist chapters cover the role of sumoylation in yeast, viruses and the tumor suppressor p53.
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Details

Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Van Gene Wilson
ISBN: 9780954523282 0954523288
OCLC Number: 55897206
Description: x, 404 pages : illustrations ; 24 cm
Contents: Ch. 1. Historical introduction to SUMO modification / Kirsten Jensen, Thomas Sternsdorf and Paul Freemont --
Ch. 2. molecular evolution of SUMO proteins / Christopher N. Larsen and Alwin Kohler --
Ch. 3. Molecular mechanism of sumoylation / Yuan Chen --
Ch. 4. SUMO proteases / Felicity Watts --
Ch. 5. SUMO E3 ligases / Andrea Pichler and Frauke Melchior --
Ch. 6. Unraveling the SUMO-2/3 conjugation and de-conjugation pathways / Hisato Saitoh --
Ch. 7. Sumoylation in yeast / Yoshiko Kikuchi --
Ch. 8. PML nuclear bodies and sumoylation / Valerie Lallemand-Breitenbach and Hugues de The --
Ch. 9. SUMO modification and nucleocytoplasmic transport / Michael J. Matunis --
Ch. 10. Control of gene expression by SUMO / David Girdwood, Michael H. Tatham and Ronald T. Hay --
Ch. 11. Viruses and sumoylation / German Rosas-Acosta and Van G. Wilson --
Ch. 12. Sumoylation of tumor suppressor p53 and of its ubiquitin ligase, Mdm2 / Hideyo Yasuda.
Responsibility: editd by Van G. Wilson.
More information:

Abstract:

This volume presents information on the history, evolution and mechanisms of sumoylation, discusses SUMO proteases, ligases and conjugation pathways, and reviews the impact on modification and nucleocytoplasmic transport, PML nuclear bodies, and transcriptional regulation. Specialist chapters cover the role of sumoylation in yeast, viruses and the tumor suppressor p53.

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