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Superantigens

Author: B Fleischer; H O Sjögren
Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 1991.
Series: Current topics in microbiology and immunology, 174.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
This volume is concerned with "superantigens", a class of molocules that areknown to be the most potent stimulators of T lymphocytes. Prototypes are theenterotoxins and the toxic-shock-syndrome toxin produced by Staphylococcus aureus. The chapters discuss the molecular biology and genetics of different superantigens and their biological and clinical significance.
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Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: B Fleischer; H O Sjögren
ISBN: 9783642509988 3642509983
OCLC Number: 851826112
Description: 1 online resource (x, 137 pages 13 illustrations).
Contents: Molecular Genetics of Pyrogenic Exotoxin "Superantigens" of Group A Streptococci and Staphylococcus aureus.- T Cell Recognition of Superantigens.- T Cell Activation by Superantigens-Dependence on MHC Class II Molecules.- The Human T Cell Response to Mitogenic Microbial Exotoxins.- Toxic Shock Syndrome Toxin-1, Toxic Shock, and the Immune System.- Staphylococcal Enterotoxin-Dependent Cell-Mediated Cytotoxicity.- CD4/CD8 Coreceptor-Independent Costimulator-Dependent Triggering of SEB-Reactive Murine T Cells.- The Immunobiology of Mycoplasma arthritidis and its Superantigen MAM.- The Anti-CD3-Induced Syndrome: A Consequence of Massive In Vivo Cell Activation.
Series Title: Current topics in microbiology and immunology, 174.
Responsibility: edited by Bernhard Fleischer, Hans Olov Sjögren.
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Abstract:

This volume is concerned with "superantigens", a class of molocules that areknown to be the most potent stimulators of T lymphocytes. Prototypes are theenterotoxins and the toxic-shock-syndrome toxin produced by Staphylococcus aureus. The chapters discuss the molecular biology and genetics of different superantigens and their biological and clinical significance.

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