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Surgical research

Author: Wiley W Souba; Douglas W Wilmore
Publisher: San Diego, CA : Academic Press, 2001.
Edition/Format:   Print book : EnglishView all editions and formats
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With the changes in the health care industry, surgeons face increasing pressure to devote their time to their clinical activities, thus limiting their research efforts. This work covers topics  Read more...

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Additional Physical Format: Surgical research [Ressource électronique] / edited by Wiley W. Souba and Douglas W. Wilmore.
Amsterdam : Elsevier B.V., [2001]. (Medicine and Dentistry)
978-0-08-054214-0
(ABES)132105063
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Wiley W Souba; Douglas W Wilmore
ISBN: 0126553300 9780126553307
OCLC Number: 45863014
Description: xxxii, 1460 pages : illustrations (some color) ; 29 cm
Contents: Getting started --
Assessing available information --
Organizing and preliminary planning for surgical research --
Writing a protocol: animals, humans, and use of biologic, chemical, and radiologic agents --
Grantsmanship --
Informed consent and the protection of human research subjects: historical perspectives and guide to current United States regulations --
Animal care and maintenance --
Funding strategies and agencies: academic-industrial relationships; intellectual property --
Statistical considerations --
Use of nonexperimental studies to evaluate surgical procedures and other interventions: the challenge of risk adjustment --
Measuring surgical outcomes --
Design of clinical trials --
Using administrative data for clinical research --
Research in the intensive care unit: ethical and methodological issues --
Research in the operating room --
Effects of age and gender --
Strategies, principles, and techniques using transgenic and knockout mouse models --
Tissue culture, cell growth, and analysis --
Hematopoietic stem cells: basic concepts and applications to surgical research --
Basic molecular biological methods in surgical research: genetic library construction, screening, and DNA sequencing --
Transcription --
Signal transduction and apoptosis --
Mechanisms and regulation of eukaryotic protein synthesis --
Organelle studies: mitochondria, golgi, and endoplasmic reticulum --
Membrane biology and biophysics --
Molecular epidemiology: beyond gene discovery to clinical diagnostic tools. Shock models: hemorrhage --
Scoring systems for trauma research --
Blunt trauma models: fractures, chest trauma, head injury, soft-tissue trauma, and abdominal trauma --
Trauma models for studying the influence of gender and aging --
Animal models of burn injury --
Wound care models --
Models of adult respiratory distress syndrome --
aspiration --
Tumor angiogenesis --
Approaches to adoptive immunotherapy --
Metastasis: biology and experimental models --
Cancer genetics --
Cancer gene therapy --
Active immunotherapy for cancer --
Gastrointestinal motility --
Models of intestinal secrection and absorption --
Surgical models of inflammatory bowel disease --
Intestinal regeneration and adaptation models --
Minimally invasive surgery --
Experimental models and endpoints for studies of intestinal ischemia-reperfusion injury --
Gut barrier failure --
Developmental studies in the gastrointestinal tract. Animal models of liver failure --
Portal hypertension and portacaval shunt --
Animal models of liver regeneration --
Animal models for the study of hepatocyte transplantation --
Biliary stone formation --
Models for the study of pancreatitis --
Models of endocrine insufficiency --
Animal models in transplantation --
Models to study surgical nutrition and metabolism --
Stable isotopes --
Body composition --
Energetics --
Models of protein metabolism --Membrane transport of nutrients --
Models of wound healing in growth factor studies --
Animal models of sepsis and the multiple organ dysfunction syndrome --
The immuno-inflammatory response --
Antibiotic trials --
Scoring systems for sepsis and the multiple organ dysfunction syndrome --
Cytokine biology --
Biology of nitric oxide: measurement, modulation, and models --
Endothelial cell and smooth muscle cell biology in vascular disease --
Coagulation biology --
Endovascular research: stents --
Noninvasive vascular measurements --
Techniques to study microcirculation --
Blood substitutes in surgery --
Research models in pediatric surgery --
Research in fetal surgery --
Research in plastic surgery --
Research methods in neurosurgery --Research in urologic surgery --
Research in cardiac surgery --
Research in orthopedic surgery --
Statistical analysis --
specific statistical tests: indications for use. Data presentation: how to write and submit abstracts and papers --
Audiovisual communications as a research skill --
rganizing and managing meetings and conferences --
The management and organization of a surgical research laboratory --
History and philosophy of surgical research --
The surgical research program as a business enterprise --
Nobel laureates in surgery --
Surgical education research --
Mathematical modeling --
Information resource discovery for surgeons: databases and the Internet --
How to review a manuscript --
Academic surgical mentoring --
Ethics and surgical research --
The National Institutes of Health: procedures and performance --
Measuring the performance of surgical research --
Virtual reality and surgery --
Surgeons and health services research --
From idea to product: financing and regulatory issues in product development.
Responsibility: edited by Wiley W. Souba, Douglas W. Wilmore.
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"The editors have brought together nearly 200 authors, whose bibliography represents a 'who's who' of North American academic surgery. With this large faculty the editors have crafted 100 chapters, Read more...

 
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