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Systemic Treatment of Prostate Cancer

Author: Alan Horwich
Publisher: Oxford : OUP Oxford, 2010.
Series: Oxford oncology library.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Prostate cancer is one of the commonest cancers in men in the western world, and the prevalence is rising currently due to improvements in screening and treatment. Serum PSA represents a useful marker of disease. It has frequently a long natural history, creating the opportunities for multiple sequential therapeutic interventions. For patients with high risk local disease or with metastases, endocrine therapy is  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Horwich, Alan.
Systemic Treatment of Prostate Cancer.
Oxford : OUP Oxford, ©2010
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Alan Horwich
ISBN: 9780191575815 019157581X 1283348330 9781283348331
OCLC Number: 763157034
Description: 1 online resource (102 pages).
Contents: Biological principles of hormone therapy --
PSA as a marker of progression and response in advanced prostate cancer --
Neo-adjuvant and adjuvant hormone therapy for high-risk localized prostate cancer --
Systemic treatment of recurrence after local therapies --
First-line hormone therapy for metastatic prostate cancer --
Second- and third-line hormone therapies --
Chemotherapy for metastatic prostate cancer --
Role of bisphosphonates in the systemic treatment of prostate cancer --
Systemic isotope therapy of bone metastasis --
Biological targets and new drug development for prostate cancer.
Series Title: Oxford oncology library.

Abstract:

Prostate cancer is one of the commonest cancers in men in the western world, and the prevalence is rising currently due to improvements in screening and treatment. Serum PSA represents a useful marker of disease. It has frequently a long natural history, creating the opportunities for multiple sequential therapeutic interventions. For patients with high risk local disease or with metastases, endocrine therapy is central to management. Hormone ablation has long been the mainstay ofendocrine therapy in this group of patients, though anti-androgens, oestrogens and corticosteroids can also cause r.

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