RT Web Page DB /z-wcorg/ DS http://worldcat.org ID 763157034 LA English UL http://public.eblib.com/EBLPublic/PublicView.do?ptiID=797725 T1 Systemic Treatment of Prostate Cancer A1 Horwich, Alan., PB OUP Oxford PP Oxford YR 2010 SN 9780191575815 019157581X AB Prostate cancer is one of the commonest cancers in men in the western world, and the prevalence is rising currently due to improvements in screening and treatment. Serum PSA represents a useful marker of disease. It has frequently a long natural history, creating the opportunities for multiple sequential therapeutic interventions. For patients with high risk local disease or with metastases, endocrine therapy is central to management. Hormone ablation has long been the mainstay ofendocrine therapy in this group of patients, though anti-androgens, oestrogens and corticosteroids can also cause r.