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A systems biology approach to blood

Author: Seth J Corey; Marek Kimmel; Joshua N Leonard
Publisher: New York : Springer, [2014] ©2014
Series: Advances in experimental medicine and biology, v. 844.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

The blood system is multi-scale, from the organism to the organs to cells to intracellular signaling pathways to macromolecule interactions.

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Additional Physical Format: Online version:
Systems biology approach to blood.
New York : Springer, [2014]
(OCoLC)897810372
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Seth J Corey; Marek Kimmel; Joshua N Leonard
ISBN: 9781493920945 1493920944
OCLC Number: 889166215
Description: ix, 403 pages : illustrations (some color) ; 24 cm.
Contents: Part I: Basic components. Systems hematology: an introduction / Seth Joel Corey, Marek Kimmel and Joshua N. Leonard --
Quantification and modeling of stem cell-niche interaction / Axel Krinner and Ingo Roeder --
Erythropoiesis: from molecular pathways to system properties / Miroslav Koulnis, Ermelinda Porpiglia, Daniel Hidalgo and Merav Socolovsky --
Systems biology of megakaryocytes / Alexis Kaushansky and Kenneth Kaushansky --
Systems biology of platelet-vessel wall interactions / Yolande Chen, Seth Joel Corey, Oleg V. Kim and Mark S. Alber --
Systems approach to phagoycte production and activation: neutrophils and monocytes / Hrishikesh M. Mehta, Taly Glaubach and Seth Joel Corey --
part II. Physiological processes. Stochasticity and determinism in models of hematopoiesis / Marek Kimmel --
Systems analysis of high-throughput data / Rosemary Braun --
Developing a systems-based understanding of hematopoietic stem cell cycle control / Ka Tat Siu and Alex C. Minella --
A systems biology approach to iron metabolism / Julia Chifman, Reinhard Laubenbacher and Suzy V. Torti --
Innate immunity in disease: insights from mathematical modeling and analysis / Nabil Azhar and Yoram Vodovotz --
Modeling biomolecular site dynamics in immunoreceptor signaling systems / Lily A. Chylek, Bridget S. Wilson and William S. Hlavacek --
Structure and function of platelet receptors initiating blood clotting / Elizabeth E. Gardiner and Robert K. Andrews --
Part III: Clinical applications / --
Understanding and treating cytopenia through mathematical modeling / Jinzhi Lei and Michael C. Mackey --
Drug resistance / Cristian Tomasetti --
Etiology and treatment of hematological neoplasms: stochastic mathematical models / Tomas Radivoyevitch, Huamin Li and Rainer K. Sachs --
Assessing hematopoietic (stem- ) cell behavior during regenerative pressure / Thomas Stiehl, Anthony D. Ho and Anna Marciniak-Czochra --
Engineered cell-based therapies: a vanguard of design-driven medicine / Rachel M. Dudek, Yishan Chuang and Joshua N. Leonard --
Part IV: Epilogue. A systems approach to blood disorders / Pankaj Qasba --
Index.
Series Title: Advances in experimental medicine and biology, v. 844.
Responsibility: Seth J. Corey, Marek Kimmel, Joshua N. Leonard, editors.
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