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Systems biology in toxicology and environmental health

Author: Rebecca C Fry
Publisher: London, England : Academic Press, 2015. ©2015
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Systems Biology in Environmental Health: From the Genome to the Epigenome brings a systems biological perspective to recent findings that link environmental exposures to human disease. In addition to introductory chapters on molecular and cellular biology, toxicology, and computational biology, the book provides an assessment of systems-based tools that evaluate environmental health risks. This includes an overview  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Systems biology in toxicology and environmental health.
London, England : Academic Press, ©2015
xii, 272 pages
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Rebecca C Fry
ISBN: 9780128015681 0128015683
OCLC Number: 912325120
Description: 1 online resource (272 pages) : illustrations (some color)
Contents: Chapter 1: Introduction to systems biologyChapter 2: Biology basicsChapter 3: From the genome to epigenome: fundamental conceptsChapter 4: Tools and technologies used in systems biologyChapter 5: Environmental contaminantsChapter 7: Environmental contaminants, inflammation-associated pathways and diseaseChapter 8: Environmental contaminants, apoptosis-associated pathways and diseaseChapter 9: Environmental contaminants, DNA damage and repair pathways and diseaseChapter 10: Environmental contaminants and hormone response and disease Chapter 11: The systems perspective
Responsibility: edited by Rebecca C. Fry, University of North Carolina at Chapel Hill, Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, Chapel Hill, NC, USA.

Abstract:

Systems Biology in Environmental Health: From the Genome to the Epigenome brings a systems biological perspective to recent findings that link environmental exposures to human disease. In addition to introductory chapters on molecular and cellular biology, toxicology, and computational biology, the book provides an assessment of systems-based tools that evaluate environmental health risks. This includes an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. The book then highlights environmental toxicants relevant to human health and disease, various high-throughput technologies, and computational methods, finally delving into the biological pathways associated with disease and the developmental origins of disease as it relates to environmental contaminants.

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"...begins with a review of the biochemical basics of genomics and proteomics to establish a foundation for exploring applied examples of systems biology in environmental health and Read more...

 
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