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Systems biology of tuberculosis

Author: Johnjoe McFadden; Dany J V Beste; Andrzej Kierzek
Publisher: New York : Springer, [2013] ©2013
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
"Tuberculosis remains one of the world's biggest killers responsible for more than a million deaths each year. New drugs and new vaccines are urgently needed to tackle the disease. This book describes the application of this century's first new science, systems biology, to the study of tuberculosis. After introducing the basic principles of systems biology, successive chapters describe how systems-based approaches  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Printed version:
Systems biology of tuberculosis.
New York ; London : Springer, 2013
(OCoLC)839309366
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Johnjoe McFadden; Dany J V Beste; Andrzej Kierzek
ISBN: 9781461449669 1461449669
OCLC Number: 822578267
Description: 1 online resource (xv, 226 pages) : illustrations (chiefly color)
Contents: Modeling Mycobacterium tuberculosis H37Rv in silico / Neema Jamshidi, Aarash Bordbar, Bernhard Palsson --
Software platform for metabolic network reconstruction of Mycobacterium tuberculosis / Samik Ghosh, Yukiko Matsuoka, Yoshiyuki Asai --
Probing gene regulatory networks to decipher host-pathogen interactions / Kanury V.S. Rao, Dhiraj Kumar, Shekhar C. Mande --
Metabolism of Mycobacterium tuberculosis / Dany J.V. Beste, Johnjoe McFadden Ph. D. --
Protein-protein interaction in the -omics era: understanding Mycobacterium tuberculosis function / Adrie J.C. Steyn, D. Mai, V. Saini, A. Farhana --
Host-pathogen interactions / Simon J. Waddell, Axel von Kamp, Steffen Klamt --
A systems biology approach for understanding granuloma formation and function in tuberculosis / Mohammad Fallahi-Sichani Ph. D., Simeone Marino Ph. D. --
Stochastic gene expression in bacterial pathogens: a mechanism for persistence? / Andrea Rocco Ph. D., Andrzej Kierzek Ph. D. --
Drug discovery / Nagasuma Chandra --
Immunological biomarkers for tuberculosis: potential for a combinatorial approach / Richard Pine, Yuri Bushkin, Maria Laura Gennaro.
Responsibility: Johnjoe McFadden, Dany J.V. Beste, Andrzej M. Kierzek, editors.

Abstract:

The book provides the reader with an account of how the new science of systems biology is providing novel insights into the ancient scourge of tuberculosis. It also describes how systems biology can  Read more...

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