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Systems biology : properties of reconstructed networks

Author: Bernhard Palsson
Publisher: Cambridge ; New York : Cambridge University Press, 2006.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
The new discipline of sytems biology examines how genome sequences interact and form networks. This text describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites for this text are knowledge of linear algebra and biochemistry.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Palsson, Bernhard.
Systems biology.
Cambridge ; New York : Cambridge University Press, 2006
(DLC) 2005035008
(OCoLC)62421240
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Bernhard Palsson
ISBN: 0521859034 9780521859035 0511145128 9780511145124 1601197608 9781601197603 9780511790515 0511790511
OCLC Number: 68904088
Description: 1 online resource (xii, 322 p.) : ill.
Contents: 1. Introduction --
2. Basic concepts in systems biology --
3. Metabolic networks --
4. Transcriptional regulatory networks --
5. Signaling networks --
6. Basic features of the stoichiometric matrix --
7. Topological properties --
8. Fundamental subspaces of S --
9. The (right) null space of S --
10. The left null space of S --
11. The row and column spaces of S --
12. Dual causality --
13. Properties of solution spaces --
14. Sampling solution spaces --
15. Finding functional states --
16. Parametric sensitivity --
17. Epilogue.
Responsibility: Bernhard Ø. Palsson.
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Abstract:

This 2001 textbook in systems biology describes how to model networks, how to determine their properties and how to relate these to phenotypic functions.  Read more...

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'... [deserves] serious attention from any quantitative scientist or physicist who hopes to learn about modern biology ... a welcome departure from the typical biology textbook ... a very readable Read more...

 
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