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Systems biology : properties of reconstructed networks

Autore: Bernhard Palsson
Editore: Cambridge ; New York : Cambridge University Press, 2006.
Edizione/Formato:   eBook : Document : EnglishVedi tutte le edizioni e i formati
Banca dati:WorldCat
Sommario:
The new discipline of sytems biology examines how genome sequences interact and form networks. This text describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites for this text are knowledge of linear algebra and biochemistry.
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Genere/forma: Electronic books
Informazioni aggiuntive sul formato: Print version:
Palsson, Bernhard.
Systems biology.
Cambridge ; New York : Cambridge University Press, 2006
(DLC) 2005035008
(OCoLC)62421240
Tipo materiale: Document, Risorsa internet
Tipo documento: Internet Resource, Computer File
Tutti gli autori / Collaboratori: Bernhard Palsson
ISBN: 0521859034 9780521859035 0511145128 9780511145124 1601197608 9781601197603 9780511790515 0511790511 9780511146473 0511146477 0511146035 9780511146039 1280347066 9781280347061
Numero OCLC: 68904088
Descrizione: 1 online resource (xii, 322 pages) : illustrations
Contenuti: 1. Introduction --
2. Basic concepts in systems biology --
3. Metabolic networks --
4. Transcriptional regulatory networks --
5. Signaling networks --
6. Basic features of the stoichiometric matrix --
7. Topological properties --
8. Fundamental subspaces of S --
9. The (right) null space of S --
10. The left null space of S --
11. The row and column spaces of S --
12. Dual causality --
13. Properties of solution spaces --
14. Sampling solution spaces --
15. Finding functional states --
16. Parametric sensitivity --
17. Epilogue.
Responsabilità: Bernhard Ø. Palsson.
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Abstract:

This textbook in systems biology describes how to model networks, how to determine their properties and how to relate these to phenotypic functions.  Per saperne di più…

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