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Systems biology : properties of reconstructed networks

Autore: Bernhard Palsson
Editore: Cambridge ; New York : Cambridge University Press, 2006.
Edizione/Formato:   eBook : Document : EnglishVedi tutte le edizioni e i formati
Banca dati:WorldCat
Sommario:
The new discipline of sytems biology examines how genome sequences interact and form networks. This text describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites for this text are knowledge of linear algebra and biochemistry.
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Genere/forma: Electronic books
Informazioni aggiuntive sul format: Print version:
Palsson, Bernhard.
Systems biology.
Cambridge ; New York : Cambridge University Press, 2006
(DLC) 2005035008
(OCoLC)62421240
Tipo materiale: Document, Risorsa internet
Tipo documento: Internet Resource, Computer File
Tutti gli autori / Collaboratori: Bernhard Palsson
ISBN: 0521859034 9780521859035 0511145128 9780511145124 1601197608 9781601197603 9780511790515 0511790511
Numero OCLC: 68904088
Descrizione: 1 online resource (xii, 322 p.) : ill.
Contenuti: 1. Introduction --
2. Basic concepts in systems biology --
3. Metabolic networks --
4. Transcriptional regulatory networks --
5. Signaling networks --
6. Basic features of the stoichiometric matrix --
7. Topological properties --
8. Fundamental subspaces of S --
9. The (right) null space of S --
10. The left null space of S --
11. The row and column spaces of S --
12. Dual causality --
13. Properties of solution spaces --
14. Sampling solution spaces --
15. Finding functional states --
16. Parametric sensitivity --
17. Epilogue.
Responsabilità: Bernhard Ø. Palsson.
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Abstract:

This 2001 textbook in systems biology describes how to model networks, how to determine their properties and how to relate these to phenotypic functions.  Per saperne di più…

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'... [deserves] serious attention from any quantitative scientist or physicist who hopes to learn about modern biology ... a welcome departure from the typical biology textbook ... a very readable Per saperne di più…

 
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