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Systems biology : properties of reconstructed networks

Auteur: Bernhard Palsson
Uitgever: Cambridge ; New York : Cambridge University Press, 2006.
Editie/Formaat:   eBoek : Document : EngelsAlle edities en materiaalsoorten bekijken.
Database:WorldCat
Samenvatting:
The new discipline of sytems biology examines how genome sequences interact and form networks. This text describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites for this text are knowledge of linear algebra and biochemistry.
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Genre/Vorm: Electronic books
Aanvullende fysieke materiaalsoort: Print version:
Palsson, Bernhard.
Systems biology.
Cambridge ; New York : Cambridge University Press, 2006
(DLC) 2005035008
(OCoLC)62421240
Genre: Document, Internetbron
Soort document: Internetbron, Computerbestand
Alle auteurs / medewerkers: Bernhard Palsson
ISBN: 0521859034 9780521859035 0511145128 9780511145124 1601197608 9781601197603 9780511790515 0511790511 9780511146473 0511146477 0511146035 9780511146039 1280347066 9781280347061
OCLC-nummer: 68904088
Beschrijving: 1 online resource (xii, 322 pages) : illustrations
Inhoud: 1. Introduction --
2. Basic concepts in systems biology --
3. Metabolic networks --
4. Transcriptional regulatory networks --
5. Signaling networks --
6. Basic features of the stoichiometric matrix --
7. Topological properties --
8. Fundamental subspaces of S --
9. The (right) null space of S --
10. The left null space of S --
11. The row and column spaces of S --
12. Dual causality --
13. Properties of solution spaces --
14. Sampling solution spaces --
15. Finding functional states --
16. Parametric sensitivity --
17. Epilogue.
Verantwoordelijkheid: Bernhard Ø. Palsson.
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'... [deserves] serious attention from any quantitative scientist or physicist who hopes to learn about modern biology ... a welcome departure from the typical biology textbook ... a very readable Meer lezen...

 
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