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T cell receptors

Author: John I Bell; M J Owen; Elizabeth Simpson, Dr.
Publisher: Oxford ; New York : Oxford University Press, 1995.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

The T cell receptor is the structure on T lymphocytes that recognizes cell-bound antigen in association with MHC class I or class II antigens. This study explores the biochemical, functional and  Read more...

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Additional Physical Format: Online version:
T cell receptors.
Oxford ; New York : Oxford University Press, 1995
(OCoLC)604049692
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: John I Bell; M J Owen; Elizabeth Simpson, Dr.
ISBN: 0192624180 9780192624185 0192624199 9780192624192
OCLC Number: 32205679
Description: xx, 483 pages, [6] pages of plates : illustrations (some color) ; 24 cm
Contents: Introduction: Historical overview. 1: Development of T cells in the thymus. 2: The function of aBT cells and the role of the co-receptor molecule, CD4 and CD8. 3: T cell specificity and function. 4: Emergence of the T cell receptor repertoire. 5: The human T cell receptor repertoire. 6: T cell activation. 7: Transgenesis and the T cell receptor. 8: Superantigens and tolerance. 9: Src - related kinases and their receptors in T cell activation. 10: Organisation of the human TCRB gene complex. 11: Genomic organisation of T cell receptor genes in the mouse. 12: Nature of variation among variable genes. 13: T cell receptor V(D)J recombination: Mechanisms and developmental regulation. 14: Allelic exclusion of T cell antigen receptor genes. 15: Plasticity of the TCR/CD3 complex. 16: The immune recognition unit: The TCR/peptide/MHC complex. 17: A structural model of a bacterial superantigen binding to MHC class II and T cell receptors. 18: Biosynthesis of MHC products and its relevance for antigen presentation. Appendix A1 - Nomanclative. Appendix A2 - Sequences
Responsibility: edited by John I. Bell, Michael J. Owen, and Elizabeth Simpson.
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