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Targeted Therapies in Oncology, Second Edition.

Author: Giuseppe Giaccone; Jean-Charles Soria
Publisher: Hoboken : Taylor and Francis, 2013.
Edition/Format:   eBook : Document : English : 2nd edView all editions and formats
Summary:
Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edition provides a concise timely panorama of existing targeted  Read more...
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Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Giuseppe Giaccone; Jean-Charles Soria
ISBN: 9781842145463 1842145460
OCLC Number: 861537936
Description: 1 online resource (486 pages)
Contents: Role of Next-Generation Sequencing Technologies; Siddhartha Devarakonda, Daniel Morgensztern, and Ramaswamy GovindanSignal Transduction Inhibitors of the HER Family; Christina Brzezniak, Corey Carter, Anish Thomas, and Giuseppe GiacconeHER2 Inhibition and Clinical Achievements; Berta Sousa, J. Ribeiro, and Fatima CardosoInhibiting the Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway; Simona Wagner and Janet E. DanceyBRAF and MEK Inhibitors; Lidia Robert and Antoni RibasKIT and KIT Inhibitors; Jean-Yves Blay, Armelle Dufresne, Olfa Derbel, and Isabelle Ray-CoquardTargeting the Fibroblast Growth Factor Receptor Pathway in Human Cancer; Maria Vittoria Dieci and Fabrice AndreAnaplastic Lymphoma Kinase; Aparna Rao and Benjamin SolomonMET Inhibitors; Apoorva Chawla, Ravi Salgia, and Victoria M. VillaflorTargeting Stem Cells; Marcello Maugeri-Sacca and Ruggero De MariaThe Cancer Super-Chaperone Hsp90: Its Posttranslational Regulation and Drug Targeting; Annerleim Walton-Diaz, Sahar Khan, Jane B. Trepel, Mehdi Mollapour, and Len NeckersTargeting Apoptosis Pathways; Pamela M. Holland, David Reese, and Jeffrey WiezorekTargeting Angiogenesis; Sophie Postel-Vinay and Jean-Pierre ArmandAntivascular Agents; Gianluca Del Conte and Cristiana SessaImmunotherapy: Monoclonal Antibodies (CTLA4, PD-1, PD-L1, IL-18, and IL-21); Patrick M. Forde and Julie R. BrahmerVaccine Therapy and Integration with Other Modalities; Benedetto Farsaci, Peter S. Kim, James W. Hodge, Claudia Palena, James L. Gulley, and Jeffrey SchlomHistone Deacetylase Inhibitors as Targeted Therapies; Alexandra Zimmer, Arup Chakraborty, Robert W. Robey, and Susan E. BatesCompounds Targeting Androgen Pathways; Aurelius Omlin, Carmel Pezaro, and Johann de BonoTargeting DNA Repair: PARP and Chk1 Inhibitors; Peter Stephens and Ruth PlummerInhibitors Targeting Mitosis; Dan L. Sackett, Edina Komlodi-Pasztor, and Tito FojoIndex

Abstract:

Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edition provides a concise timely panorama of existing targeted therapies and progress into future anticancer treatments. These therapies notably include:Targeted agents of immune checkpoints<L.

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"...an outstanding collection of work ..."-Yun Yen, MD, PhD, City of Hope Comprehensive Cancer Center for Doody's Review Service

 
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