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Taxane anticancer agents : basic science and current status : developed from symposia sponsored by the Divisions of Chemical Health and Safety, Medicinal Chemistry, and Organic Chemistry at the 207th National Meeting of the American Chemical Society, San Diego, California, March 13-18, 1994

Author: Gunda I Georg; American Chemical Society. Division of Chemical Health and Safety.; American Chemical Society. Division of Medicinal Chemistry.; American Chemical Society. Division of Organic Chemistry.; American Chemical Society. Meeting
Publisher: Washington, DC : American Chemical Society, 1995.
Series: ACS symposium series, 583.
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Summary:

This work presents a general overview of the development of taxol as an anticancer drug, including the discovery, initial development, current status, supply issues and recent clinical developments.  Read more...

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Genre/Form: Congresses
Conference papers and proceedings
Congrès
Additional Physical Format: Online version:
Taxane anticancer agents.
Washington, DC : American Chemical Society, 1995
(OCoLC)622868201
Material Type: Conference publication, Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Gunda I Georg; American Chemical Society. Division of Chemical Health and Safety.; American Chemical Society. Division of Medicinal Chemistry.; American Chemical Society. Division of Organic Chemistry.; American Chemical Society. Meeting
ISBN: 0841230730 9780841230736
OCLC Number: 31378411
Description: xiii, 353 pages : illustrations, map ; 24 cm.
Contents: Overview of paclitaxel research : progress on many fronts / Matthew Suffness --
Paclitaxel : from discovery to clinic / Monroe E. Wall and Mansukh C. Wani --
Current status of clinical trials with paclitaxel and docetaxel / F.A. Holmes, A.P. Kudelka, J.J. Kavanagh, M.H. Huber, J.A. Ajani, and V. Valero --
The Pacific yew environmental impact statement / S.J. Campbell and S.A. Whitney --
Paclitaxel biosynthesis : the early steps / Rodney Croteau, Mehri Hezari, Jerry Hefner, Alfred Koepp, and Norman G. Lewis --
Bioactive metabolites of the endophytic fungi of Pacific yew, Taxus brevifolia : paclitaxel, taxanes, and other bioactive compounds / Andrea Stierle, Donald Stierle, Gary Strobel, Gary Bignami, and Paul Grothaus --
Metabolism of taxoid drugs / M. Vuilhorgne, C. Gaillard, G.J. Sanderink, I. Royer, B. Monsarrat, J. Dubois, and M. Wright --
Pharmacology and antitumor effect of novel paclitaxel formulations / R.M. Straubinger, A. Sharma, U.S. Sharma, and S.V. Balasubramanian --
Phosphatase-activated prodrugs of paclitaxel / D.M. Vyas, Y. Ueda, H. Wong, J.D. Matiskella, S. Hauck, A.B. Mikkilineni, Vittorio Farina, W.C. Rose, and A.M. Casazza --
Microtubule polymerization dynamics, mitotic block, and cell death by paclitaxel at low concentrations / Mary Ann Jordon and Leslie Wilson --
Photoincorporation of a paclitaxel photoaffinity analogue into the N-terminal 31 amino acids of [beta]-tubulin / Susan Band Horwitz, Srinivasa Rao, Nancy E. Krauss, Julie M. Heerding, Charles S. Swindell, Israel Ringel, and George A. Orr --
Paclitaxel, a mimetic of bacterial lipopolysaccharide (LPS) in murine macrophages / S.N. Vogel, J.M. Carboni, and C.L. Manthey --
The roles of the cytoskeleton in steroidogenesis : the actions of paclitaxel and other cytoskeletal agents / Pamela J. Massey, Michael R. Caudle, Jeffrey K. Keenan, and Thomas T. Chen --
Chemistry and structure-activity relationships of taxoids with modified skeletons / F. Guéritte-Voegelein, D. Guénard, J. Dubois, A. Wahl, R. Marder, R. Müller, M. Lund, L. Bricard, and P. Potier --
Recent advances in the chemistry and structure-activity relationships of paclitaxel / David G.I. Kingston --
Medicinal chemistry of paclitaxel : chemistry, structure-activity relationships, and conformational analysis / Gunda I. Georg, Geraldine C.B. Harriman, David G. Vander Velde, Thomas C. Boge, Zacharia S. Cheruvallath, Apurba Datta, Michael Hepperle, Haeil Park, Richard H. Himes, and Lalith Jayasinghe --
Practical semisynthesis and antimitotic activity of docetaxel and side-chain analogues / A. Commerçon, J.D. Bourzat, E. Didier, and François Lavelle --
Paclitaxel structure-activity relationships and core skeletal rearrangements / Shu-Hui Chen and Vittorio Farina --
Syntheses and structure-activity relationships of new taxoids / Iwao Ojima, Young Hoon Park, Ivana Fenoglio, Olivier Duclos, Chung-Ming Sun, Scott D. Kuduk, Martine Zucco, Giovanni Appendino, Paula Pera, Jean M. Veith, Ralph J. Bernacki, Marie-Christine Bissery, C. Combeau, P. Vrignaud, J.F. Riou, and François Lavelle --
Chemistry and antitumor activity of 9(R)-dihydrotaxanes / L.L. Klein, L. Li, C.M. Yeung, C.J. Maring, S.A. Thomas, D.J. Grampovnik, and J.J. Plattner --
The total synthesis of paclitaxel starting with camphor / Robert A. Holton, Carmen Somoza, Hyeong-Baik Kim, Feng Liang, Ronald J. Biediger, P. Douglas Boatman, Mitsuru Shindo, Chase C. Smith, Soekchan Kim, Hossain Nadizadeh, Yukio Suzuki, Chunlin Tao, Phong Vu, Suhan Tang, Pingsheng Zhang, Krishna K. Murthi, Lisa N. Gentile, and Jyanwei H. Liu --
The total synthesis of paclitaxel by assembly of the ring system / K.C. Nicolaou and R.K. Guy --
Toward the design of a convergent practical route to all classes of taxanes / Leo A. Paquette --
The pinene path to taxanes : genesis and evolution of a strategy for synthesis / Paul A. Wender, Neil F. Badham, Simon P. Conway, Paul E. Floreancig, Timothy E. Glass, Jonathan B. Houze, Nancy E. Krauss, Daesung Lee, Daniel G. Marquess, Paul L. McGrane, Wei Meng, Thomas P. Mucciaro, Michel Mühlebach, Michael G. Natchus, Takeshi Ohkuma, Bernd Peschke, David B. Rawlins, Anthony J. Shuker, Jim C. Sutton, Richard E. Taylor, Katsuhiko Tomooka, and Ludger A. Wessjohann.
Series Title: ACS symposium series, 583.
Responsibility: Gunda I. Georg, editor [and others].
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