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Telomeres

Author: Titia De Lange; Vicki Lundblad; Elizabeth H Blackburn
Publisher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, ©2006.
Series: Cold Spring Harbor monograph series, 45.
Edition/Format:   Print book : English : 2nd edView all editions and formats
Summary:
Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging.
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Additional Physical Format: Online version:
Telomeres.
Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, ©2006
(OCoLC)607560874
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Titia De Lange; Vicki Lundblad; Elizabeth H Blackburn
ISBN: 0879697342 9780879697341
OCLC Number: 61179545
Description: viii, 576 pages : illustrations (some color) ; 24 cm.
Contents: A history of telomere biology --
The telomerase ribonucleoprotein particle --
Telomerase biochemistry and biogenesis --
Telomerase and human cancer --
Modeling cancer and aging in the telomerase-deficient mouse --
Telomerase deficiency and human disease --
Telomerase-independent maintenance of mammalian telomeres --
Telomerase-independent telomere maintenance in yeast --
Meiotic telomeres --
Telomere position effect : silencing near the end --
The structural biology of telomeres --
Budding yeast telomeres --
Mammalian telomeres --
Drosophila telomeres --
Ciliate telomeres --
Fission yeast telomeres --
Plant telomeres.
Series Title: Cold Spring Harbor monograph series, 45.
Responsibility: edited by Titia de Lange, Vicki Lundblad, Elizabeth Blackburn.
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Abstract:

Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging.

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