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Ten years of progress in GW/P body research

ผู้แต่ง: Edward K L Chan; Marvin J Fritzler
สำนักพิมพ์: New York, NY : Springer, ©2013.
ชุด: Advances in experimental medicine and biology, 768.
ครั้งที่พิมพ์/รูปแบบ:   หนังสืออีเล็กทรอนิกส์ : เอกสาร : ภาษาอังกฤษดูครั้งที่พิมพ์และรูปแบบ
ฐานข้อมูล:WorldCat
สรุป:
GW bodies are novel cytoplasmic foci that were discovered and named by Dr. Chan's group in 2002. These bodies are now known to be active cytoplasmic foci involved with the new gene regulation process mediated by microRNA that leads to translational repression and mRNA degradation. The detailed biological functions of these cytoplasmic structures are still being uncovered and the idea for this book is to provide the  อ่านมากขึ้น…
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ประเภท/แบบฟอร์ม Electronic books
ขนิดวัสดุ: เอกสาร, ทรัพยากรอินแทอร์เน็ต
ประเภทของเอกสาร: แหล่งข้อมูลอินเทอร์เน็ต, ไฟล์คอมพิวเตอร์
ผู้แต่งทั้งหมด : ผู้แต่งร่วม Edward K L Chan; Marvin J Fritzler
ISBN: 9781461451075 1461451078 146145106X 9781461451068
OCLC Number: 822997159
หมายเหตุ: Includes index.
คำอธิบาย: 1 online resource.
สารบัญ: Introduction: The GW Body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology / Edward K. L. Chan, Marvin J. Fritzler --
The Discovery of GW Bodies / Marvin J. Fritzler, Edward K. L. Chan --
The Discovery and Analysis of P Bodies / Saumya Jain, Roy Parker --
Autoantibodies to Argonaute 2 (Su Antigen) / Minoru Satoh, Jason Y. F. Chan --
GW/P-Bodies and Autoimmune Disease / Donald B. Bloch, Rita A. Nobre --
Function of GW182 and GW Bodies in siRNA and miRNA Pathways / Bing Yao, Songqing Li, Edward K. L. Chan --
Post-transcriptional Stimulation of Gene Expression by MicroRNAs / Sooncheol Lee, Shobha Vasudevan --
Gawky (GW) is the Drosophila melanogaster GW182 Homologue / Jing Li, Tom C. Hobman, Andrew J. Simmonds --
The Role of GW182 Proteins in miRNA-Mediated Gene Silencing / Joerg E. Braun, Eric Huntzinger --
Quantifying Argonaute Proteins In and Out of GW/P-Bodies: Implications in microRNA Activities / Anthony K. L. Leung, Phillip A. Sharp --
Deadenylation and P-Bodies / Chyi-Ying A. Chen, Ann-Bin Shyu --
Relationship of GW/P-Bodies with Stress Granules / Georg Stoecklin, Nancy Kedersha --
Relationship of Other Cytoplasmic Ribonucleoprotein Bodies (cRNPB) to GW/P Bodies / Joanna J. Moser, Marvin J. Fritzler --
An SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182 / Joanna J. Moser, Edward K. L. Chan --
Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research / Edward K. L. Chan, Bing Yao. Preface --
The GW body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology --
The Discovery of GW Bodies --
The Discovery and Analysis of P Bodies --
Autoantibodies to Argonaute 2 (Su antigen) --
GW/P Bodies and Autoimmune Disease --
Function of GW182 and GW Bodies in siRNA and miRNA Pathways --
Post-Transcriptional Stimulation of Gene Expression by MicroRNAs --
Gawky (Gw) is the Drosophila Melanogaster GW182 Homologue --
The Role of GW182 Proteins in miRNA-mediated Gene Silencing --
Quantifying Argonaute Proteins in and out of GW/P-bodies: Implications in microRNA Activities --
Deadenylation and P-bodies --
Relationship of GW/P-bodies with Stress Granules --
Relationship of other Cytoplasmic Ribonucleoprotein (RNP) Bodies to GW/P Bodies --
A SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182 --
Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research --
Index.
ชื่อชุด: Advances in experimental medicine and biology, 768.
ความรับผิดชอบ: Edward K. L. Chan, Marvin J. Fritzler, editors.
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บทคัดย่อ:

This book investigates GW bodies, novel cytoplasmic foci known to be involved with a new gene regulation process mediated by microRNA, that leads to translational repression and mRNA degradation.  อ่านมากขึ้น…

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    โดย xerxes70 ปรับปรุง 2013-04-22
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