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Therapeutic Fc Fusion Proteins

Author: Steven Mark Chamow
Publisher: Weinheim : Wiley-Blackwell, ©2014.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

This first guide to Fc-Fusion proteins gives a complete overview of the design, manufacturing, quality control, case studies and future trends of this promising class of biopharmaceuticals.

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Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Steven Mark Chamow
ISBN: 9783527675272 3527675272 9783527675296 3527675299 1306256178 9781306256179
OCLC Number: 866839740
Notes: Includes index.
Description: 1 online resource
Contents: Introduction: Antibody Structure and Function / Arvind Rajpal, Pavel Strop, Yik Andy Yeung, Javier Chaparro-Riggers, Jaume Pons --
Methods of Production for Fc-Fusion Proteins. Fc-Fusion Protein Expression Technology / Jody D Berry, Catherine Yang, Janean Fisher, Ella Mendoza, Shanique Young, Dwayne Stupack --
Cell Culture-Based Production / Yao-Ming Huang, Rashmi Kshirsagar, Barbara Woppmann, Thomas Ryll --
Downstream Processing of Fc-Fusion Proteins / Abhinav A Shukla, Uwe Gottschalk --
Formulation, Drug Product, and Delivery: Considerations for Fc-Fusion Proteins / Wenjin Cao, Deirdre Murphy Piedmonte, Margaret Speed Ricci, Ping Y Yeh --
Quality by Design Applied to a Fc-Fusion Protein: A Case Study / Alex Eon-Duval, Ralf Gleixner, Pascal Valax, Miroslav Soos, Benjamin Neunstoecklin, Massimo Morbidelli, Hervé Broly --
Analytical Methods Used to Characterize Fc-Fusion Proteins / Esohe Idusogie, Michael Mulkerrin --
Case Studies of Therapeutic Fc-Fusion Proteins. Introduction to Therapeutic Fc-Fusion Proteins / Jody D Berry --
Alefacept / Deborah A Farson --
Etanercept / Johanna Grossman, Steven M Chamow --
Abatacept and Belatacept / Robert J Peach --
Aflibercept / Angela L Linderholm, Steven M Chamow --
Recombinant Factor VIII- and Factor IX-Fc Fusions / Robert T Peters, Judy R Berlfein.
Responsibility: edited by Steven M. Chamow [and others].

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"In conclusion, this is an excellent book that combines the theory and practice of the Fc-fusion protein and peptides. It is a valuable book for those readers working in the development of biologics Read more...

 
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