doorgaan naar inhoud
Therapeutic kinase inhibitors Voorbeeldweergave van dit item
SluitenVoorbeeldweergave van dit item
Bezig met controle...

Therapeutic kinase inhibitors

Auteur: Ingo K Mellinghoff; Charles L Sawyers
Uitgever: Heidelberg : Springer Verlag, 2012.
Serie: Current topics in microbiology and immunology, v. 355.
Editie/Formaat:   eBoek : Document : EngelsAlle edities en materiaalsoorten bekijken.
Database:WorldCat
Samenvatting:
Cancer drug development is currently undergoing a profound shift. Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as "chemotherapy" and still the backbone of most cancer treatment regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which provide growth and survival signals to  Meer lezen...
Beoordeling:

(nog niet beoordeeld) 0 met beoordelingen - U bent de eerste

Onderwerpen
Meer in deze trant

 

Zoeken naar een online exemplaar

Links naar dit item

Zoeken naar een in de bibliotheek beschikbaar exemplaar

&AllPage.SpinnerRetrieving; Bibliotheken met dit item worden gezocht…

Details

Genre/Vorm: Electronic books
Aanvullende fysieke materiaalsoort: Print version:
Therapeutic kinase inhibitors.
Heidelberg: Springer Verlag, 2012
(OCoLC)773671497
Genre: Document, Internetbron
Soort document: Internetbron, Computerbestand
Alle auteurs / medewerkers: Ingo K Mellinghoff; Charles L Sawyers
ISBN: 9783642282966 3642282962 9781283865258 1283865254
OCLC-nummer: 821823527
Beschrijving: 1 online resource (x, 234 p.) : ill.
Inhoud: Setting up a Kinase Discovery and Development Project / Gideon Bollag --
Drug Efficacy Testing in Mice / William Y. Kim, Norman E. Sharpless --
Gastrointestinal Stromal Tumors / Cristina Antonescu --
EGFR Mutant Lung Cancer / Yixuan Gong, William Pao --
Targeting Oncogenic BRAF in Human Cancer / Christine A. Pratilas, Feng Xing, David B. Solit --
Beyond BRAF in Melanoma / Adil Daud, Boris C. Bastian --
JAK-Mutant Myeloproliferative Neoplasms / Ross L. Levine --
Will Kinase Inhibitors Make it as Glioblastoma Drugs? / Ingo K. Mellinghoff, Nikolaus Schultz, Paul S. Mischel --
Predictive Genomic Biomarkers / Rakesh Kumar, Rafael G. Amado --
Epigenetic Biomarkers / Timothy A. Chan, Stephen B. Baylin --
Adjuvant Trials of Targeted Agents: The Newest Battleground in the War on Cancer / Robert L. Cohen.
Serietitel: Current topics in microbiology and immunology, v. 355.
Verantwoordelijkheid: Ingo K. Mellinghoff, Charles L. Sawyers, editors ; responsible series editor: Peter K. Vogt.

Fragment:

Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as "chemotherapy" and still the backbone of most cancer treatment regimens, are  Meer lezen...

Beoordelingen

Beoordelingen door gebruikers
Beoordelingen van GoodReads worden opgehaald...
Bezig met opvragen DOGObooks-reviews...

Tags

U bent de eerste.
Bevestig deze aanvraag

Misschien heeft u dit item reeds aangevraagd. Selecteer a.u.b. Ok als u toch wilt doorgaan met deze aanvraag.

Gekoppelde data


Primary Entity

<http://www.worldcat.org/oclc/821823527> # Therapeutic kinase inhibitors
    a schema:MediaObject, schema:Book, schema:CreativeWork ;
    library:oclcnum "821823527" ;
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/gw> ;
    library:placeOfPublication <http://experiment.worldcat.org/entity/work/data/1108176972#Place/heidelberg> ; # Heidelberg
    schema:about <http://experiment.worldcat.org/entity/work/data/1108176972#Topic/neoplasms_drug_therapy> ; # Neoplasms--drug therapy
    schema:about <http://experiment.worldcat.org/entity/work/data/1108176972#Topic/drug_discovery> ; # Drug Discovery
    schema:about <http://dewey.info/class/615.798/e22/> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/1108176972#Topic/antineoplastic_agents_therapeutic_use> ; # Antineoplastic Agents--therapeutic use
    schema:about <http://id.worldcat.org/fast/810595> ; # Antineoplastic agents
    schema:about <http://experiment.worldcat.org/entity/work/data/1108176972#Topic/protein_kinase_inhibitors_therapeutic_use> ; # Protein Kinase Inhibitors--therapeutic use
    schema:about <http://experiment.worldcat.org/entity/work/data/1108176972#Topic/medical_pharmacology> ; # MEDICAL / Pharmacology
    schema:about <http://experiment.worldcat.org/entity/work/data/1108176972#Topic/adenosine_triphosphate_therapeutic_use> ; # Adenosine Triphosphate--therapeutic use
    schema:about <http://id.loc.gov/authorities/subjects/sh85019497> ; # Cancer--Chemotherapy
    schema:about <http://id.worldcat.org/fast/845327> ; # Cancer--Chemotherapy
    schema:bookFormat schema:EBook ;
    schema:contributor <http://viaf.org/viaf/284230729> ; # Ingo K. Mellinghoff
    schema:contributor <http://viaf.org/viaf/234383555> ; # Charles L. Sawyers
    schema:datePublished "2012" ;
    schema:description "Cancer drug development is currently undergoing a profound shift. Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as "chemotherapy" and still the backbone of most cancer treatment regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which provide growth and survival signals to cancer cells by transferring phosphate groups from Adenosine-5'-triphosphate (ATP) to other proteins, lipids, nucleotides, and carbohydrates. This book summarizes the current state of kinase inhibitor therapy for cancer. Successful drug development relies on the expertise and dedication of many experts. To reflect this team approach to finding new kinase inhibitors and defining their optimal use for cancer treatment, the editors invited experts in academia and pharmaceutical industry to share their insights into various aspects of this process, ranging from the first chemical screens, to preclinical testing and disease-focused clinical drug development. The editors hope these lessons will be instructive for the novice as well as the expert." ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/1108176972> ;
    schema:genre "Electronic books" ;
    schema:inLanguage "en" ;
    schema:isPartOf <http://worldcat.org/issn/0070-217X> ; # Current topics in microbiology and immunology ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/773671497> ;
    schema:name "Therapeutic kinase inhibitors" ;
    schema:numberOfPages "234" ;
    schema:productID "821823527" ;
    schema:publication <http://www.worldcat.org/title/-/oclc/821823527#PublicationEvent/heidelberg_springer_verlag_2012> ;
    schema:publisher <http://experiment.worldcat.org/entity/work/data/1108176972#Agent/springer_verlag> ; # Springer Verlag
    schema:url <http://dx.doi.org/10.1007/978-3-642-28296-6> ;
    schema:url <http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=511429> ;
    schema:url <http://lib.myilibrary.com?id=417775> ;
    schema:url <http://swb.eblib.com/patron/FullRecord.aspx?p=972191> ;
    schema:workExample <http://dx.doi.org/10.1007/978-3-642-28296-6> ;
    schema:workExample <http://worldcat.org/isbn/9781283865258> ;
    schema:workExample <http://worldcat.org/isbn/9783642282966> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/821823527> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/1108176972#Agent/springer_verlag> # Springer Verlag
    a bgn:Agent ;
    schema:name "Springer Verlag" ;
    .

<http://experiment.worldcat.org/entity/work/data/1108176972#Topic/adenosine_triphosphate_therapeutic_use> # Adenosine Triphosphate--therapeutic use
    a schema:Intangible ;
    schema:name "Adenosine Triphosphate--therapeutic use" ;
    .

<http://experiment.worldcat.org/entity/work/data/1108176972#Topic/antineoplastic_agents_therapeutic_use> # Antineoplastic Agents--therapeutic use
    a schema:Intangible ;
    schema:name "Antineoplastic Agents--therapeutic use" ;
    .

<http://experiment.worldcat.org/entity/work/data/1108176972#Topic/medical_pharmacology> # MEDICAL / Pharmacology
    a schema:Intangible ;
    schema:name "MEDICAL / Pharmacology" ;
    .

<http://experiment.worldcat.org/entity/work/data/1108176972#Topic/neoplasms_drug_therapy> # Neoplasms--drug therapy
    a schema:Intangible ;
    schema:name "Neoplasms--drug therapy" ;
    .

<http://experiment.worldcat.org/entity/work/data/1108176972#Topic/protein_kinase_inhibitors_therapeutic_use> # Protein Kinase Inhibitors--therapeutic use
    a schema:Intangible ;
    schema:name "Protein Kinase Inhibitors--therapeutic use" ;
    .

<http://id.loc.gov/authorities/subjects/sh85019497> # Cancer--Chemotherapy
    a schema:Intangible ;
    schema:name "Cancer--Chemotherapy" ;
    .

<http://id.worldcat.org/fast/810595> # Antineoplastic agents
    a schema:Intangible ;
    schema:name "Antineoplastic agents" ;
    .

<http://id.worldcat.org/fast/845327> # Cancer--Chemotherapy
    a schema:Intangible ;
    schema:name "Cancer--Chemotherapy" ;
    .

<http://lib.myilibrary.com?id=417775>
    rdfs:comment "Connect to MyiLibrary resource." ;
    .

<http://viaf.org/viaf/234383555> # Charles L. Sawyers
    a schema:Person ;
    schema:familyName "Sawyers" ;
    schema:givenName "Charles L." ;
    schema:name "Charles L. Sawyers" ;
    .

<http://viaf.org/viaf/284230729> # Ingo K. Mellinghoff
    a schema:Person ;
    schema:familyName "Mellinghoff" ;
    schema:givenName "Ingo K." ;
    schema:name "Ingo K. Mellinghoff" ;
    .

<http://worldcat.org/isbn/9781283865258>
    a schema:ProductModel ;
    schema:description "MyiLibrary" ;
    schema:isbn "1283865254" ;
    schema:isbn "9781283865258" ;
    .

<http://worldcat.org/isbn/9783642282966>
    a schema:ProductModel ;
    schema:description "electronic bk." ;
    schema:isbn "3642282962" ;
    schema:isbn "9783642282966" ;
    .

<http://worldcat.org/issn/0070-217X> # Current topics in microbiology and immunology ;
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/821823527> ; # Therapeutic kinase inhibitors
    schema:issn "0070-217X" ;
    schema:name "Current topics in microbiology and immunology ;" ;
    schema:name "Current topics in microbiology and immunology," ;
    .

<http://www.worldcat.org/oclc/773671497>
    a schema:CreativeWork ;
    rdfs:label "Therapeutic kinase inhibitors." ;
    schema:description "Print version:" ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/821823527> ; # Therapeutic kinase inhibitors
    .


Content-negotiable representations

Venster sluiten

Meld u aan bij WorldCat 

Heeft u geen account? U kunt eenvoudig een nieuwe gratis account aanmaken.