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Therapeutic kinase inhibitors

ผู้แต่ง: Ingo K Mellinghoff; Charles L Sawyers
สำนักพิมพ์: Heidelberg : Springer Verlag, 2012.
ชุด: Current topics in microbiology and immunology, v. 355.
ครั้งที่พิมพ์/รูปแบบ:   หนังสืออีเล็กทรอนิกส์ : เอกสาร : ภาษาอังกฤษดูครั้งที่พิมพ์และรูปแบบ
ฐานข้อมูล:WorldCat
สรุป:
Cancer drug development is currently undergoing a profound shift. Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as "chemotherapy" and still the backbone of most cancer treatment regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which provide growth and survival signals to  อ่านมากขึ้น…
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รูปแบบทางกายภาพเพิ่มเติม Print version:
Therapeutic kinase inhibitors.
Heidelberg: Springer Verlag, 2012
(OCoLC)773671497
ขนิดวัสดุ: เอกสาร, ทรัพยากรอินแทอร์เน็ต
ประเภทของเอกสาร: แหล่งข้อมูลอินเทอร์เน็ต, ไฟล์คอมพิวเตอร์
ผู้แต่งทั้งหมด : ผู้แต่งร่วม Ingo K Mellinghoff; Charles L Sawyers
ISBN: 9783642282966 3642282962 9781283865258 1283865254
OCLC Number: 821823527
คำอธิบาย: 1 online resource (x, 234 p.) : ill.
สารบัญ: Setting up a Kinase Discovery and Development Project / Gideon Bollag --
Drug Efficacy Testing in Mice / William Y. Kim, Norman E. Sharpless --
Gastrointestinal Stromal Tumors / Cristina Antonescu --
EGFR Mutant Lung Cancer / Yixuan Gong, William Pao --
Targeting Oncogenic BRAF in Human Cancer / Christine A. Pratilas, Feng Xing, David B. Solit --
Beyond BRAF in Melanoma / Adil Daud, Boris C. Bastian --
JAK-Mutant Myeloproliferative Neoplasms / Ross L. Levine --
Will Kinase Inhibitors Make it as Glioblastoma Drugs? / Ingo K. Mellinghoff, Nikolaus Schultz, Paul S. Mischel --
Predictive Genomic Biomarkers / Rakesh Kumar, Rafael G. Amado --
Epigenetic Biomarkers / Timothy A. Chan, Stephen B. Baylin --
Adjuvant Trials of Targeted Agents: The Newest Battleground in the War on Cancer / Robert L. Cohen.
ชื่อชุด: Current topics in microbiology and immunology, v. 355.
ความรับผิดชอบ: Ingo K. Mellinghoff, Charles L. Sawyers, editors ; responsible series editor: Peter K. Vogt.

บทคัดย่อ:

Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as "chemotherapy" and still the backbone of most cancer treatment regimens, are  อ่านมากขึ้น…

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