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Therapeutic kinase inhibitors

著者: Ingo K Mellinghoff; Charles L Sawyers
出版商: Heidelberg : Springer Verlag, 2012.
丛书: Current topics in microbiology and immunology, v. 355.
版本/格式:   电子图书 : 文献 : 英语查看所有的版本和格式
数据库:WorldCat
提要:
Cancer drug development is currently undergoing a profound shift. Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as "chemotherapy" and still the backbone of most cancer treatment regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which provide growth and survival signals to  再读一些...
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类型/形式: Electronic books
附加的形体格式: Print version:
Therapeutic kinase inhibitors.
Heidelberg: Springer Verlag, 2012
(OCoLC)773671497
材料类型: 文献, 互联网资源
文件类型: 互联网资源, 计算机文档
所有的著者/提供者: Ingo K Mellinghoff; Charles L Sawyers
ISBN: 9783642282966 3642282962 9781283865258 1283865254
OCLC号码: 821823527
描述: 1 online resource (x, 234 p.) : ill.
内容: Setting up a Kinase Discovery and Development Project / Gideon Bollag --
Drug Efficacy Testing in Mice / William Y. Kim, Norman E. Sharpless --
Gastrointestinal Stromal Tumors / Cristina Antonescu --
EGFR Mutant Lung Cancer / Yixuan Gong, William Pao --
Targeting Oncogenic BRAF in Human Cancer / Christine A. Pratilas, Feng Xing, David B. Solit --
Beyond BRAF in Melanoma / Adil Daud, Boris C. Bastian --
JAK-Mutant Myeloproliferative Neoplasms / Ross L. Levine --
Will Kinase Inhibitors Make it as Glioblastoma Drugs? / Ingo K. Mellinghoff, Nikolaus Schultz, Paul S. Mischel --
Predictive Genomic Biomarkers / Rakesh Kumar, Rafael G. Amado --
Epigenetic Biomarkers / Timothy A. Chan, Stephen B. Baylin --
Adjuvant Trials of Targeted Agents: The Newest Battleground in the War on Cancer / Robert L. Cohen.
丛书名: Current topics in microbiology and immunology, v. 355.
责任: Ingo K. Mellinghoff, Charles L. Sawyers, editors ; responsible series editor: Peter K. Vogt.

摘要:

Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as "chemotherapy" and still the backbone of most cancer treatment regimens, are  再读一些...

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