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Therapeutic kinase inhibitors

作者: Ingo K Mellinghoff; Charles L Sawyers
出版商: Heidelberg : Springer Verlag, 2012.
叢書: Current topics in microbiology and immunology, v. 355.
版本/格式:   電子書 : 文獻 : 英語所有版本和格式的總覽
資料庫:WorldCat
提要:
Cancer drug development is currently undergoing a profound shift. Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as "chemotherapy" and still the backbone of most cancer treatment regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which provide growth and survival signals to  再讀一些...
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詳細書目

類型/形式: Electronic books
其他的實體格式: Print version:
Therapeutic kinase inhibitors.
Heidelberg: Springer Verlag, 2012
(OCoLC)773671497
資料類型: 文獻, 網際網路資源
文件類型: 網路資源, 電腦資料
所有的作者/貢獻者: Ingo K Mellinghoff; Charles L Sawyers
ISBN: 9783642282966 3642282962 9781283865258 1283865254
OCLC系統控制編碼: 821823527
描述: 1 online resource (x, 234 pages) : illustrations.
内容: Setting up a Kinase Discovery and Development Project / Gideon Bollag --
Drug Efficacy Testing in Mice / William Y. Kim, Norman E. Sharpless --
Gastrointestinal Stromal Tumors / Cristina Antonescu --
EGFR Mutant Lung Cancer / Yixuan Gong, William Pao --
Targeting Oncogenic BRAF in Human Cancer / Christine A. Pratilas, Feng Xing, David B. Solit --
Beyond BRAF in Melanoma / Adil Daud, Boris C. Bastian --
JAK-Mutant Myeloproliferative Neoplasms / Ross L. Levine --
Will Kinase Inhibitors Make it as Glioblastoma Drugs? / Ingo K. Mellinghoff, Nikolaus Schultz, Paul S. Mischel --
Predictive Genomic Biomarkers / Rakesh Kumar, Rafael G. Amado --
Epigenetic Biomarkers / Timothy A. Chan, Stephen B. Baylin --
Adjuvant Trials of Targeted Agents: The Newest Battleground in the War on Cancer / Robert L. Cohen.
叢書名: Current topics in microbiology and immunology, v. 355.
責任: Ingo K. Mellinghoff, Charles L. Sawyers, editors ; responsible series editor: Peter K. Vogt.

摘要:

Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as "chemotherapy" and still the backbone of most cancer treatment regimens, are  再讀一些...

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