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Three-dimensional structures of oligosaccharides.
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Three-dimensional structures of oligosaccharides.

Author: RJ Woods Affiliation: Complex Carbohydrate Research Center, University of Georgia, Athens 30602-4712, USA.
Edition/Format: Article Article : English
Publication:Current opinion in structural biology, 1995 Oct; 5(5): 591-8
Database:From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
Other Databases: ECO
Summary:
Oligosaccharides represent a particularly challenging class of molecules for conformational analysis. Recent advances in experimental and theoretical methods have begun to yield further insight into their conformational behavior; however, general rules governing their conformational preferences have not yet emerged. X-ray and NMR techniques may provide vital insights into protein-bound oligosaccharide conformations,  Read more...
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Details

Document Type: Article
All Authors / Contributors: RJ Woods Affiliation: Complex Carbohydrate Research Center, University of Georgia, Athens 30602-4712, USA.
ISSN:0959-440X
Language Note: English
Unique Identifier: 121412753
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Abstract:

Oligosaccharides represent a particularly challenging class of molecules for conformational analysis. Recent advances in experimental and theoretical methods have begun to yield further insight into their conformational behavior; however, general rules governing their conformational preferences have not yet emerged. X-ray and NMR techniques may provide vital insights into protein-bound oligosaccharide conformations, but these do not necessarily represent highly populated solution conformations. Moreover, an oligosaccharide's inherent flexibility and lack of strong intermolecular interactions places extreme demands on theoretical methods.

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