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The Thyroid

Author: William L Green
Publisher: New York : Elsevier, ©1987.
Series: Current endocrinology.
Edition/Format:   Print book : EnglishView all editions and formats

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Additional Physical Format: Online version:
New York : Elsevier, ©1987
Online version:
New York : Elsevier, ©1987
Document Type: Book
All Authors / Contributors: William L Green
ISBN: 0444010920 9780444010926
OCLC Number: 14002656
Description: xvi, 349 pages : illustrations ; 24 cm.
Contents: Foreward. Preface. Contributors. Physiology of the Thyroid Gland and its Hormones (W.L. Green). Introduction: An overview of thyroid physiology. Development and anatomy. Hormone synthesis and secretion. Fate of thyroid hormones in peripheral tissues. Neuroendocrine regulation: TSH and TRH. Actions of the thyroid hormones. References. Autoimmune Mechanisms in Thyroid Disease (B. Rapoport). Introduction. Immunologic principles in autoimmunity. Etiology of autoimmune thyroid disease. Heredity of autoimmune thyroid disease. Humoral thyroid stimulators in Graves' disease. Cell-mediated immunity and lymphocytic function in Graves' disease. Immune complexes in autoimmune thyroid diseases. Ophthalmopathy in autoimmune thyroid disease. Pretibial myxedema. Experimental models for Grave's disease. Thyroid antibodies in Hashimoto's thyroiditis. Pathogenesis of Hashimoto's thyroiditis. References. Laboratory Evaluation of Thyroid Status (R.R. Cavalieri). Introduction. Thyroidal iodine metabolism. The perchlorate test for defective intrathyroidal organification. Tests of thyroid iodine turnover and release. Estimation of stable iodine in the thyroid. Measurement of circulating thyroid hormone. Measurement of total hormone concentration. Measurement of free hormone. Tests of the hypothalamic-pituitary-thyroid axis. Metabolic indices: tests of thyroid hormone action. Achilles reflex time. Physiologic and pathologic factors influencing circulating hormone. Applications of thyroid function tests to special problems. References. Hyperthyroidism (R.D. Utiger). Introduction. Pathophysiology. Causes of hyperthyroidism. Clinical manifestations of hyperthyroidism. Laboratory diagnosis of hyperthyroidism. Treatment of hyperthyroidism. Special situations. Extrathyroidal manifestations of Graves' disease. References. Hypothyroidism (C.H. Emerson, C. Liberman, and L.E. Braverman). Introduction. Etiology, incidence, and pathogenesis. Clinical features of hypothyroidism. Effects of primary hypothyroidism on function of other endocrine glands. Laboratory diagnosis of hypothyroidism. Treatment of hypothyroidism. References. Goiter (C. Liberman, C.H. Emerson, and L.E. Braveman). Introduction. Primary goiter. Secondary goiter. Summary. References. Thyroid Neoplasia (M.C. Gershengorn, and J. Robbins). Introduction. Classification and pathologic anatomy. Etiology. Incidence. Diagnosis. Preoperative management of nodular thyroid disease. Management of radiation-exposed patients. Clinical features, natural history, and management of thyroid carcinoma. Concluding remarks. References. Index.
Series Title: Current endocrinology.
Responsibility: edited by William L. Green.


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