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To grasp the essence of life : a history of molecular biology

Author: Rudolf Hausmann
Publisher: Dordrecht ; Boston, Mass. : Kluwer Academic Pub., 2002.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

In each chapter, the development of a particular aspect of modern biology is described in a historical and logical context, not missing to take into account human aspects of the protagonists of the  Read more...

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Genre/Form: History
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Rudolf Hausmann
ISBN: 1402010923 9781402010927
OCLC Number: 51088148
Language Note: The present English version is an updated and slightly expanded translation of the German edition: " ... und wollten versuchen, das Leben zu verstehen ... Betrachtungen zur Geschichte der Molekularbiologie" Wissenschaftliche Buchgesellschaft Darmstadt; ISBN 3534115759.
Description: xii, 332 pages : illustrations ; 24 cm
Contents: Enzymes --
Cell fractionation --
Emil Fischer, Franz Hofmeister, and the peptide bond --
Spatial structures of polypeptides --
X-ray diffraction analysis --
Pascual Jordan's mistake --
Genes --
Escherichia coli: an example of a self-replicating machine --
A brief digression: where does the energy come from? --
Mendel --
Chromosome maps --
The early biochemistry of the cell nucleus --
One Gene--One Enzyme --
The replica plate technique (Lederberg & Lederberg, 1952) --
Proof of contact between parental cells during bacterial conjugation--and the discovery of transduction --
Phages --
Bacteriophages --
The quest for the origin of mutations: Luria and Delbruck's fluctuation test --
Phage-directed protein synthesis --
The Double Helix --
Double Helix: the Anticlimax --
A corollary of Watson and Crick's model: the insight that errors in base-pairing can lead to mutations --
The replication mode of DNA --
Denaturation, renaturation, and hybridization of DNA --
Avery? Hershey? --
The transforming principle is DNA --
Hershey & Chase's (1952) blender experiment --
The Code Craze --
One mutation alters hemoglobin in only one amino acid --
Linearity ... Colinearity --
Protein Synthesis in vitro. How did it all start? --
Polypeptide synthesis proceeds from the amino- to the carboxy-terminal --
The Code in vitro --
How does polypeptide synthesis occur on the ribosome? --
Inside the Institut Pasteur, Part I: Prophage and the Fertility Factor F --
Parasites at the genetic level --
Inside the Institut Pasteur, Part II: Interrupted Mating.
Other Titles: Und wollten versuchen, das Leben zu erstehen.
Responsibility: by Rudolf Hausmann ; translated by Celma and Rudolf Hausmann.
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