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Toxicity of alternatives to chlorofluorocarbons : HFC-134a and HCFC-123

Author: National Research Council (U.S.). Subcommittee to Review Toxicity of Alternatives to Chlorofluorocarbons,
Publisher: Washington, D.C. : National Academy Press, 1996.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
As part of the effort to phase out the use of stratospheric ozone-depleting substances, such as chlorofluorocarbons (CFCs) and Halon gases, the U.S. Navy is planning to substitute hydrofluorocarbon (HFC)-134a for the refrigerant CFC-12, and the Air Force is planning to substitute hydrochlorofluorocarbon (HCFC)-123 for the fire suppressant Halon 1211. The Navy asked the National Research Council (NRC) to review the  Read more...
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Genre/Form: Electronic books
Computer network resources
Additional Physical Format: Print version:
Toxicity of alternatives to chlorfluorocarbons HFC-134a and HCFC-123.
Washington, DC : National Academy Press, 1996
(OCoLC)35771789
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: National Research Council (U.S.). Subcommittee to Review Toxicity of Alternatives to Chlorofluorocarbons,
ISBN: 0309572010 9780309572019
OCLC Number: 567831797
Notes: Title from title screen.
Description: 1 online resource : illustrations
Responsibility: Subcommittee to Review Toxicity of Alternatives to Chlorofluorocarbons, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council.

Abstract:

As part of the effort to phase out the use of stratospheric ozone-depleting substances, such as chlorofluorocarbons (CFCs) and Halon gases, the U.S. Navy is planning to substitute hydrofluorocarbon (HFC)-134a for the refrigerant CFC-12, and the Air Force is planning to substitute hydrochlorofluorocarbon (HCFC)-123 for the fire suppressant Halon 1211. The Navy asked the National Research Council (NRC) to review the toxicity data on HFC-134a and to recommend 1-hr and 24-hr emergency exposure guidance levels (EEGLs) and 90-day continuous exposure guidance levels (CEGLs). The Air Force requested the NRC to review the adequacy of the 1-min EEGL proposed by the Air Force for HCFC-123. In addition, the U.S. Environmental Protection Agency (EPA) requested the NRC to review the suitability of current methods for detecting and quantifying the risk of cardiac sensitization from exposure to CFCs and their substitutes. The NRC assigned these tasks to its Committee on Toxicology, which established the Subcommittee to Review Toxicity of Alternatives to Chlorofluorocarbons. The subcommittee reviewed the toxicity data on the two CFC substitutes and the assessment protocol for cardiac sensitization. This report is intended to aid the Navy, the Air Force, and EPA in using CFC substitutes safely.

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