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Toxicological Effects of Methylmercury.

Author: National Research Council Staff; Committee on the Toxicological Effects of Methylmercury; Board on Environmental Studies and Toxicology Staff
Publisher: Washington : National Academies Press, 2000.
Edition/Format:   eBook : Document : EnglishView all editions and formats
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Staff, National Research Council.
Toxicological Effects of Methylmercury.
Washington : National Academies Press, ©1900
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: National Research Council Staff; Committee on the Toxicological Effects of Methylmercury; Board on Environmental Studies and Toxicology Staff
ISBN: 9780309569705 0309569702 0309071402 9780309071406
OCLC Number: 923270163
Language Note: English.
Notes: ""Poisoning Episode in Iraq""
Description: 1 online resource (368 pages)
Contents: ""Toxicological Effects of Methylmercury""; ""Copyright""; ""PREFACE""; ""Contents""; ""EXECUTIVE SUMMARY""; ""THE CHARGE TO THE COMMITTEE""; ""THE COMMITTEE'S APPROACH TO ITS CHARGE""; ""THE COMMITTEE'S EVALUATION""; ""Health Effects of Methylmercury""; ""Determination of the Critical Study for the RfD""; ""Estimation of Dose and Biological Variability""; ""Modeling the Dose-Response Relationships""; ""Public-Health Implications""; ""RESEARCH NEEDS""; ""RECOMMENDATIONS""; ""1 INTRODUCTION""; ""SOURCES OF HG""; ""FATE AND TRANSPORT""; ""HEALTH EFFECTS""; ""EXPOSURE EVENTS AND STUDIES"" ""SUMMARY OF RISK ASSESSMENTS FOR MEHG""""SCIENTIFIC CONTROVERSIES AND SOURCES OF UNCERTAINTY""; ""ORGANIZATION OF THE REPORT""; ""REFERENCES""; ""2 CHEMISTRY, EXPOSURE, TOXICOKINETICS, AND TOXICODYNAMICS ""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""METHODS OF CHEMICAL ANALYSIS""; ""EXPOSURES TO MEHG IN THE U.S. POPULATION""; ""TOXICOKINETICS""; ""Absorption and Distribution""; ""Methylmercury""; ""Dimethylmercury""; ""Elemental Mercury""; ""Inorganic Mercury""; ""Biotransformation""; ""Excretion""; ""MOBILIZATION OF BODY HG""; ""CHEMICAL FORMS OF HG IN TOXICITY"" ""TOXIC EFFECTS AND TARGET ORGANS""""BIOCHEMICAL MECHANISMS OF TOXICITY""; ""SUMMARY AND CONCLUSIONS""; ""RECOMMENDATIONS""; ""REFERENCES""; ""3 BIOLOGICAL VARIABILITY ""; ""AGE-RELATED SUSCEPTIBILITY""; ""GENDER DIFFERENCES""; ""GENETICS""; ""MECHANISMS OF NUTRITIONAL INFLUENCE ON MEHG HEALTH EFFECTS""; ""Dietary Interactions and Confounding""; ""Selenium""; ""Garlic""; ""Omega-3 Fatty Acids""; ""Protein""; ""Alcohol""; ""Other Foods That Might Influence Hg Uptake""; ""Vitamin E""; ""Nutrient Enhancement of Toxicity""; ""Beneficial Effects of Fish Consumption""; ""TOXICOKINETIC VARIABILITY"" ""CONCLUSIONS""""RECOMMENDATIONS""; ""REFERENCES""; ""4 DOSE ESTIMATION ""; ""DIETARY ASSESSMENT""; ""BIOMARKERS OF EXPOSURE""; ""Methylmercury in Blood""; ""Methylmercury in Hair""; ""Comparison of Biomarkers of Exposure""; ""ANALYTICAL ERROR IN BIOMARKER MEASUREMENTS""; ""EXPOSURE AND DOSE ASSESSMENT IN THE SEYCHELLES, FAROE ISLANDS, AND NEW ZEALAND STUDIES""; ""SUMMARY AND CONCLUSIONS""; ""RECOMMENDATIONS""; ""REFERENCES""; ""5 HEALTH EFFECTS OF METHYLMERCURY ""; ""CARCINOGENICITY""; ""Human Studies""; ""Animal Studies""; ""GENOTOXICITY""; ""Human Studies""; ""Animal Studies"" ""In Vitro Studies""""IMMUNOTOXICITY""; ""Human Studies""; ""Animal Studies""; ""Effects on the Adult Immune System""; ""Effects on the Developing Immune System""; ""In Vitro Studies""; ""Autoimmune Response""; ""Human Studies""; ""Animal Studies""; ""REPRODUCTIVE EFFECTS""; ""Human Studies""; ""Animal Studies""; ""RENAL TOXICITY""; ""Human Studies""; ""Animal Studies""; ""CARDIOVASCULAR EFFECTS""; ""Human Studies""; ""Animal Studies""; ""HEMATOLOGICAL EFFECTS""; ""DEVELOPING CENTRAL-NERVOUS-SYSTEM TOXICITY""; ""Human Studies""; ""High-Dose Poisonings""; ""Poisoning Episode in Japan""

Abstract:

Reviewing the health effects of methylmercury, this work discusses the estimation of mercury exposure from measured biomarkers, how differences between individuals affect mercury toxicity, and  Read more...

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