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Transcription factors in the nervous system : development, brain function and diseases

Author: Gerald Thiel
Publisher: Weinheim : Wiley-VCH, ©2006.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
Summary:
Covers neural development, neuronal survival and function on the genetic level outlines promising approaches for novel therapeutic strategies in fighting neurodegenerative disorders, such as Alzheimer's disease. Focusing on transcription factors, the text is clearly divided into three sections devoted to transcriptional control of neural development, brain function and transcriptional dysregulation induced  Read more...
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Genre/Form: Aufsatzsammlung
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Gerald Thiel
ISBN: 9783527312856 3527312854
OCLC Number: 63392895
Description: lx, 445 pages : illustrations (some color) ; 25 cm
Contents: 1. Roles of Hes bHLH factors in neural development / Ryoichiro Kageyama, Jun Hatakeyama and Toshiyuki Ohtsuka --
2. role of Pax6 in the nervous system during development and in adulthood : master control regulator or modular function? / Nicole Haubst, Jack Favor and Magdalena Gotz --
3. Phox2a and Phox2b : essential transcription factors for neuron specification and differentiation / Uwe Ernsberger and Hermann Rohrer --
4. Functions of LIM-homeodomain proteins in the development of the nervous system / Yangu Zhao, Nasir Malik and Heiner Westphal --
5. roles of serum response factor in brain development and function / Bernd Knoll and Alfred Nordheim --
6. RE-1 silencing transcription factor (REST) : regulation of neuronal gene expression via modification of the chromatin structure / Gerald Thiel and Mathias Hohl --
7. Roles of Tix1 and Tix3 and neuronal activity in controlling glutamatergic over GABAergic cell fates / Qiufu Ma and Le-ping Cheng --
8. Transcriptional control of the development of central serotonergic neurons / Zhou-Feng Chen and Yu-Qiang Ding --
9. Role of Nkx homeodomain factors in the specification and differentiation of motor neurons and oligodendrocytes / Jun Cai and Mengsheng Qiu --
10. Sox transcription factors in neural development / Michael Wegner and C. Claus Stolt --
11. role of CREB and CBP in brain function / Angel Barco and Eric R. Kandel --
12. CCAAT enhancer binding proteins in the nervous system : their role in development, differentiation, long-term synaptic plasticity, and memory / Cristina M. Alberini --
13. role of c-Jun in brain function / Gennadij Raivich and Axel Behrens --
14. Expression, function, and regulation of transcription factor MEF2 in neurons / Zixu Mao and Xuemin Wang --
15. RORa : an orphan that staggers the mind / Peter M. Gent and Bruce A. Hamilton. 16. role of NF-kB in brain function / Barbara Kaltschmidt, Ilja Mikenberg, Darius Widera and Christian Kaltschmidt --
17. Calcineurin/NFAT signaling in development and function of the nervous system / Isabella A. Graef, Gerald R. Crabtree and Fan Wang --
18. Stimulus-transcription coupling in the nervous system : the zinc finger protein Egr-1 / Oliver G. Rossler, Luisa Stefano, Inge Bouer and Gerald Thiel --
19. presenilin/g-secretase complex regulates production of transcriptional factors : effects of FAD mutations / Nikolaos K. Robakis and Philippe Marambaud --
20. Transcriptional abnormalities in Huntington's disease / Dimitri Krainc.
Responsibility: edited by Gerald Thiel.
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Abstract:

This first book to cover neural development, neuronal survival and function on the genetic level outlines promising approaches for novel therapeutic strategies in fighting neurodegenerative  Read more...

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"...this volume presents critical information for neuroscientists while also providing a valuable resource for biologists, chemists, and geneticists in related fields or in biomedical research." (The Read more...

 
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