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Transcriptional regulation in eukaryotes : concepts, strategies, and techniques
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Transcriptional regulation in eukaryotes : concepts, strategies, and techniques

Author: Michael Carey; Stephen T Smale
Publisher: Cold Spring Harbor, NY : Cold Spring Harbor Laboratory Press, ©2000.
Edition/Format:   Book : EnglishView all editions and formats
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Additional Physical Format: Online version:
Carey, Michael (Michael F.)
Transcriptional regulation in eukaryotes.
Cold Spring Harbor, NY : Cold Spring Harbor Laboratory Press, c2000
(OCoLC)645891005
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Michael Carey; Stephen T Smale
ISBN: 0879696656 9780879696658 0879695374 9780879695378 0879696354 9780879696351
OCLC Number: 42603257
Description: xxix, 640 p. : ill. ; 29 cm.
Contents: A primer on transcriptional regulation in mammalian cells --
Initial strategic issues --
Modes of regulating mRNA abundance --
Transcription initiation site mapping --
Functional assays for promoter analysis --
Identification and analysis of distant control regions --
Identifying cis-acting DNA elements within a control region --
Identification of DNA-binding proteins and isolation of their genes --
Confirming the functional importance of a protein-DNA interaction --
In vivo analysis of an endogenous control region --
Approaches for the synthesis of recombinant transcription factors --
Identifying and characterizing transcription factor domains --
Theory, characterization, and modeling of DNA binding by regulatory transcription factors --
Crude and fractionated systems for in vitro transcription --
Approaches for studying transcription complex assembly.
Responsibility: Michael Carey, Stephen T. Smale.

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