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Transporters as drug carriers : structure, function, substrates

Author: Gerhard Ecker; Peter Chiba
Publisher: Weinheim : Wiley-VCH, ©2009.
Series: Methods and principles in medicinal chemistry, v. 44.
Edition/Format:   Book : EnglishView all editions and formats
Database:WorldCat
Summary:
(Publisher-supplied data) This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with  Read more...
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Gerhard Ecker; Peter Chiba
ISBN: 9783527316618 3527316612
OCLC Number: 320496245
Description: xx, 429 pages : illustrations.
Contents: PART 1 1 The ABC Transporters: Structural Insights into Drug Transport 2 Biochemistry, Physiology, and Pharmacology of Nucleoside and Nucleobase Transporters 3 Organic Anion Transporting Polypeptides (Oatps/OATPs) 4 CNS Transporters as Drug Targets PART 2 5 Bacterial Multidrug Transporters: Molecular and Clinical Aspects 6 Pleiotropic drug resistance in yeast and fungal pathogens PART 3 7 QSAR studies on ABC-transporters: how to deal with polyspecificity 8 Drug Transporter Pharmacophores PART 4 9 Biological Membranes and Drug Transport 10 Transport at the Blood-Brain Barrier 11 Bile canalicular transporters 12 Interplay of Cytochrome P450 Isoenzymes and ABC-transporter 13 ABC-Transporter: From target to antitarget PART 3 14 A Systems Biology View of Drug Transporters 15 Drug Transporters in Health and Disease
Series Title: Methods and principles in medicinal chemistry, v. 44.
Responsibility: edited by Gerhard Ecker and Peter Chiba.
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Abstract:

This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge  Read more...

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"Overall, the book is well organized and the topics are clearly and easily accessible. This book offers many strengths ...but overall is quite worthwhile." (ChemMedChem, January 2011) "Overall, the Read more...

 
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