RT Book, Whole DB /z-wcorg/ DS http://worldcat.org ID 320496245 LA English T1 Transporters as drug carriers : structure, function, substrates A1 Ecker, Gerhard., Chiba, Peter., PB Wiley-VCH PP Weinheim YR 2009 SN 9783527316618 3527316612 AB (Publisher-supplied data) This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion. As a result, this key resource lays the foundations for understanding and investigating the molecular mechanisms for multidrug resistance in cancer cells, microbial resistance to antibiotics and pharmacokinetics in general. For anyone working with antibiotics and cancer chemotherapeutics, as well as being of prime interest to biochemists and biophysicists.