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Transporters as drug carriers : structure, function, substrates

Verfasser/in: Gerhard Ecker; Peter Chiba
Verlag: Weinheim : Wiley-VCH, ©2009.
Serien: Methods and principles in medicinal chemistry, v. 44.
Ausgabe/Format   Print book : EnglischAlle Ausgaben und Formate anzeigen
Datenbank:WorldCat
Zusammenfassung:
(Publisher-supplied data) This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with  Weiterlesen…
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Medientyp: Internetquelle
Dokumenttyp: Buch, Internet-Ressource
Alle Autoren: Gerhard Ecker; Peter Chiba
ISBN: 9783527316618 3527316612
OCLC-Nummer: 320496245
Beschreibung: xx, 429 p. : ill.
Inhalt: PART 1 1 The ABC Transporters: Structural Insights into Drug Transport 2 Biochemistry, Physiology, and Pharmacology of Nucleoside and Nucleobase Transporters 3 Organic Anion Transporting Polypeptides (Oatps/OATPs) 4 CNS Transporters as Drug Targets PART 2 5 Bacterial Multidrug Transporters: Molecular and Clinical Aspects 6 Pleiotropic drug resistance in yeast and fungal pathogens PART 3 7 QSAR studies on ABC-transporters: how to deal with polyspecificity 8 Drug Transporter Pharmacophores PART 4 9 Biological Membranes and Drug Transport 10 Transport at the Blood-Brain Barrier 11 Bile canalicular transporters 12 Interplay of Cytochrome P450 Isoenzymes and ABC-transporter 13 ABC-Transporter: From target to antitarget PART 3 14 A Systems Biology View of Drug Transporters 15 Drug Transporters in Health and Disease
Serientitel: Methods and principles in medicinal chemistry, v. 44.
Verfasserangabe: edited by Gerhard Ecker and Peter Chiba.
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Abstract:

This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge  Weiterlesen…

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