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Transporters as drug carriers : structure, function, substrates

Autore: Gerhard Ecker; Peter Chiba
Editore: Weinheim : Wiley-VCH, ©2009.
Serie: Methods and principles in medicinal chemistry, v. 44.
Edizione/Formato:   Libro : EnglishVedi tutte le edizioni e i formati
Banca dati:WorldCat
Sommario:
(Publisher-supplied data) This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with  Per saperne di più…
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Tipo materiale: Risorsa internet
Tipo documento: Book, Internet Resource
Tutti gli autori / Collaboratori: Gerhard Ecker; Peter Chiba
ISBN: 9783527316618 3527316612
Numero OCLC: 320496245
Descrizione: xx, 429 pages : illustrations.
Contenuti: PART 1 1 The ABC Transporters: Structural Insights into Drug Transport 2 Biochemistry, Physiology, and Pharmacology of Nucleoside and Nucleobase Transporters 3 Organic Anion Transporting Polypeptides (Oatps/OATPs) 4 CNS Transporters as Drug Targets PART 2 5 Bacterial Multidrug Transporters: Molecular and Clinical Aspects 6 Pleiotropic drug resistance in yeast and fungal pathogens PART 3 7 QSAR studies on ABC-transporters: how to deal with polyspecificity 8 Drug Transporter Pharmacophores PART 4 9 Biological Membranes and Drug Transport 10 Transport at the Blood-Brain Barrier 11 Bile canalicular transporters 12 Interplay of Cytochrome P450 Isoenzymes and ABC-transporter 13 ABC-Transporter: From target to antitarget PART 3 14 A Systems Biology View of Drug Transporters 15 Drug Transporters in Health and Disease
Titolo della serie: Methods and principles in medicinal chemistry, v. 44.
Responsabilità: edited by Gerhard Ecker and Peter Chiba.
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Abstract:

This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge  Per saperne di più…

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"Overall, the book is well organized and the topics are clearly and easily accessible. This book offers many strengths ...but overall is quite worthwhile." (ChemMedChem, January 2011) "Overall, the Per saperne di più…

 
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